• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

伪狂犬病病毒感染期间核碱性蛋白的变化

Changes in nuclear basic proteins during pseudorabies virus infection.

作者信息

Stevens J G, Kado-Boll G J, Haven C B

出版信息

J Virol. 1969 May;3(5):490-7. doi: 10.1128/JVI.3.5.490-497.1969.

DOI:10.1128/JVI.3.5.490-497.1969
PMID:5786178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC375799/
Abstract

As a preliminary study to investigation of the possible role played by basic proteins in the genetic regulation of virus-infected cells, acid-extractable proteins synthesized during pseudorabies virus infection were investigated. The synthesis of histones was found to decrease in a gradual manner, and arrest was complete by 6 hr after infection. Five virus-induced acid-extractable proteins appeared in nuclei of infected cells after 4 hr of infection. Four of these proteins were virus structural proteins; one was not. All these proteins contained tryptophan and, therefore, were not "classic" histones.

摘要

作为研究碱性蛋白在病毒感染细胞基因调控中可能作用的初步研究，对伪狂犬病病毒感染期间合成的酸可提取蛋白进行了研究。发现组蛋白的合成逐渐减少，感染后6小时完全停止。感染4小时后，五种病毒诱导的酸可提取蛋白出现在受感染细胞的细胞核中。其中四种蛋白是病毒结构蛋白，一种不是。所有这些蛋白都含有色氨酸，因此不是“经典”组蛋白。

相似文献

1
Changes in nuclear basic proteins during pseudorabies virus infection.伪狂犬病病毒感染期间核碱性蛋白的变化
J Virol. 1969 May;3(5):490-7. doi: 10.1128/JVI.3.5.490-497.1969.
2
Virus-induced proteins in pseudorabies-infected cells. I. Acid-extractable proteins of the nucleus.伪狂犬病感染细胞中的病毒诱导蛋白。I. 细胞核的酸可提取蛋白。
J Virol. 1973 Jun;11(6):815-22. doi: 10.1128/JVI.11.6.815-822.1973.
3
Synthesis of proteins in cells infected with herpesvirus. 8. Absence of virus-induced alteration of nuclear membrane in arginine-deprived cells.疱疹病毒感染细胞中蛋白质的合成。8. 精氨酸缺乏细胞中病毒诱导的核膜改变缺失。
Virology. 1972 Jul;49(1):102-11. doi: 10.1016/s0042-6822(72)80011-4.
4
Synthesis of proteins in cells infected with herpesvirus. VII. Lack of migration of structural viral proteins to the nucleus of arginine-deprived cells.疱疹病毒感染细胞中蛋白质的合成。VII. 结构病毒蛋白在精氨酸缺乏细胞中无法迁移至细胞核。
Virology. 1971 Jul;45(1):53-60. doi: 10.1016/0042-6822(71)90112-7.
5
Synthesis of proteins in cells infected with herpesvirus. 3. Relative amino acid content of various proteins formed after infection.疱疹病毒感染细胞中蛋白质的合成。3. 感染后形成的各种蛋白质的相对氨基酸含量。
Virology. 1970 Jan;40(1):90-101. doi: 10.1016/0042-6822(70)90382-x.
6
Synthesis of proteins in cells infected with herpesvirus. IX. Sulfated proteins.感染疱疹病毒的细胞中蛋白质的合成。IX. 硫酸化蛋白质。
Virology. 1973 Sep;55(1):94-102. doi: 10.1016/s0042-6822(73)81011-6.
7
Early functions of the genome of herpesvirus. I. Characterization of the RNA synthesized in cycloheximide-treated, infected cells.疱疹病毒基因组的早期功能。I. 环己酰亚胺处理的感染细胞中合成的RNA的特性
Virology. 1971 Dec;46(3):877-89. doi: 10.1016/0042-6822(71)90088-2.
8
Synthesis of proteins in cells infected with herpesvirus. II. Flow of structural viral proteins from cytoplasm to nucleus.感染疱疹病毒的细胞中蛋白质的合成。II. 病毒结构蛋白从细胞质到细胞核的流动。
Virology. 1969 Jan;37(1):56-61. doi: 10.1016/0042-6822(69)90306-7.
9
Synthesis of proteins in cells infected with herpesvirus. I. Structural viral proteins.疱疹病毒感染细胞中蛋白质的合成。I. 病毒结构蛋白。
Virology. 1969 Jan;37(1):49-55. doi: 10.1016/0042-6822(69)90305-5.
10
Nuclear protein synthesis in hamster kidney cells: the effect of pseudorabies virus infection.仓鼠肾细胞中的核蛋白合成：伪狂犬病病毒感染的影响。
Arch Gesamte Virusforsch. 1974;44(2):84-91. doi: 10.1007/BF01250216.

引用本文的文献

1
Transcriptomic analysis of the dialogue between Pseudorabies virus and porcine epithelial cells during infection.伪狂犬病病毒感染期间与猪上皮细胞对话的转录组学分析
BMC Genomics. 2008 Mar 10;9:123. doi: 10.1186/1471-2164-9-123.
2
Incorporation of Cystine by Yeast Cells of Histoplasma capsulatum.荚膜组织胞浆菌酵母细胞胱氨酸的掺入。
Infect Immun. 1970 Aug;2(2):169-74. doi: 10.1128/iai.2.2.169-174.1970.
3
Restricted replication of herpes simplex virus in spinal ganglia of resistant mice is accompanied by an early infiltration of immunoglobulin G-bearing cells.单纯疱疹病毒在抗性小鼠脊髓神经节中的复制受限，同时伴有携带免疫球蛋白G的细胞早期浸润。
Infect Immun. 1983 May;40(2):752-8. doi: 10.1128/iai.40.2.752-758.1983.
4
Structural analysis of the capsid polypeptides of herpes simplex virus types 1 and 2.1型和2型单纯疱疹病毒衣壳多肽的结构分析
J Virol. 1980 May;34(2):521-31. doi: 10.1128/JVI.34.2.521-531.1980.
5
Transformation of mammalian cells by crude histones.粗制组蛋白对哺乳动物细胞的转化作用。
Br J Cancer. 1971 Jun;25(2):280-3. doi: 10.1038/bjc.1971.35.
6
Nuclear protein synthesis in hamster kidney cells: the effect of pseudorabies virus infection.仓鼠肾细胞中的核蛋白合成：伪狂犬病病毒感染的影响。
Arch Gesamte Virusforsch. 1974;44(2):84-91. doi: 10.1007/BF01250216.
7
Virus-induced proteins in pseudorabies-infected cells. I. Acid-extractable proteins of the nucleus.伪狂犬病感染细胞中的病毒诱导蛋白。I. 细胞核的酸可提取蛋白。
J Virol. 1973 Jun;11(6):815-22. doi: 10.1128/JVI.11.6.815-822.1973.
8
Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intra-axonal transport of infection.小鼠疱疹性神经炎和神经节炎的发病机制：感染轴突内运输的证据
Infect Immun. 1973 Feb;7(2):272-88. doi: 10.1128/iai.7.2.272-288.1973.
9
Restriction of herpes simplex virus by macrophages. An analysis of the cell-virus interaction.巨噬细胞对单纯疱疹病毒的限制。细胞-病毒相互作用的分析。
J Exp Med. 1971 Jan 1;133(1):19-38. doi: 10.1084/jem.133.1.19.

本文引用的文献

1
The Biology of Isolated Chromatin: Chromosomes, biologically active in the test tube, provide a powerful tool for the study of gene action.孤立染色质的生物学：在试管中具有生物活性的染色体为研究基因作用提供了一个有力的工具。
Science. 1968 Jan 5;159(3810):47-56. doi: 10.1126/science.159.3810.47.
2
The cytoplasmic synthesis of histones in hela cells and its temporal relationship to DNA replication.海拉细胞中组蛋白的细胞质合成及其与DNA复制的时间关系。
Proc Natl Acad Sci U S A. 1967 Feb;57(2):409-16. doi: 10.1073/pnas.57.2.409.
3
KINETICS OF SYNTHESIS OF VARIOUS TYPES OF ANTIGENIC PROTEINS IN CELLS INFECTED WITH PSEUDORABIES VIRUS.伪狂犬病病毒感染细胞中各类抗原蛋白的合成动力学
J Bacteriol. 1965 May;89(5):1328-34. doi: 10.1128/jb.89.5.1328-1334.1965.
4
MECHANISM OF INHIBITION OF CELLULAR DNA SYNTHESIS BY PSEUDORABIES VIRUS.伪狂犬病病毒抑制细胞DNA合成的机制
Virology. 1965 Jan;25:22-9. doi: 10.1016/0042-6822(65)90247-3.
5
AMINO ACID REQUIREMENTS OF HERPES SIMPLEX VIRUS IN HUMAN CELLS.人细胞中单纯疱疹病毒的氨基酸需求
J Bacteriol. 1964 Mar;87(3):609-13. doi: 10.1128/jb.87.3.609-613.1964.
6
Electron microscopic studies on the architecture of animal viruses.动物病毒结构的电子显微镜研究。
Cold Spring Harb Symp Quant Biol. 1962;27:25-47. doi: 10.1101/sqb.1962.027.001.006.
7
The pattern of viral and cellular DNA synthesis in pseudorabies virus-infected cells in the logarithmic phase of growth.生长对数期感染伪狂犬病病毒的细胞中病毒和细胞DNA合成的模式。
Virology. 1963 Feb;19:205-14. doi: 10.1016/0042-6822(63)90010-2.
8
Amino acid metabolism in mammalian cell cultures.哺乳动物细胞培养中的氨基酸代谢
Science. 1959 Aug 21;130(3373):432-7. doi: 10.1126/science.130.3373.432.
9
RNA metabolism in the HeLa cell nucleus.海拉细胞核中的RNA代谢
J Mol Biol. 1966 May;17(1):117-30. doi: 10.1016/s0022-2836(66)80098-0.
10
Quantitative distribution of histone components in the pea plant.豌豆植株中组蛋白成分的定量分布
Biochemistry. 1968 Feb;7(2):575-85. doi: 10.1021/bi00842a010.