[Studies on the dependence of intrafollicular pressure on the pressure in the intraovarian-vascular-system and tissue, carried out in vitro on human ovaries (author's transl)].

The intrafollicular, intraovarian and intraarterial hydrostatic pressures were measured in vitro on human ovaries in the vollicular ripening phase. It has been established that in the vascular system as well as in the intraovarian tissues pressure variations occur spontaneously. Thus for example under, the influence of epinephrine, norepinephrine, prostaglandine F2 alpha and oxytocine, the tonicity of the vascular system increases and does so the number of spontaneous contractions rather noticeably, particularly under the influence of prostaglandine F2alpha, and under the various catecholamines an increase of frequency and amplitude has been observed. Any increase of pressure in the intraovarian vascular system and tissues will effect all the follicles not yet in the preovulatorian phase, in which they cause a similar pressure increase. However, follicles imminently preovulatorian have not shown such pressure increase because the increase of the "liquor folliculi" runs parallel to the increasing elasticity of the follicle walls. The findings are discussed in this article with a particular view of the biophysical aspects of ovulation.