Vyklický L, Rudomin P, Zajac F E, Burke R E
Science. 1969 Jul 11;165(3889):184-6. doi: 10.1126/science.165.3889.184.
Pulses of intense radiant heat applied to the plantar pad of unanesthetized spinal cats produced negative dorsal root potentials, increased excitability of cutaneous A fibers, and marked activation of ipsilateral flexor motoneurons. The same effects were obtained during cold block of A fiber conduction in the appropriate peripheral nerve. We conclude that adequate noxious activation of cutaneous C fibers depolarizes cutaneous A fibers.
