Brown H M, McIntyre D
Acta Allergol. 1977 Oct;32(5):321-32.
Nasal provocation testing using a measured dose of dry grass pollen has been used as a method of controlling the amount of injection treatment required to achieve decreased sensitivity to grass pollen. This could seldom be shown at the usual top dose of 10,000 P.N.U., but by repeating the top dose until the reaction was negative, complete freedom from pollenosis was achieved in most cases. Strict criteria for assessment of results were used. Conventional dosage regimens produced only 27 percent excellent results, but 94 percent of those patients who became demonstrably nasal test-negative were completely or almost completely free from symptoms in the pollen season.
使用定量干草花粉进行鼻激发试验，已被用作一种控制实现对草花粉敏感性降低所需注射治疗量的方法。在通常的10,000个花粉单位的最高剂量下，很少能显示出这种效果，但通过重复最高剂量直至反应呈阴性，大多数情况下可实现完全摆脱花粉症。采用了严格的结果评估标准。传统的给药方案仅产生27%的优异结果，但在花粉季节，94%经证实鼻试验呈阴性的患者完全或几乎完全没有症状。
