Yamashita T, Arnold W, Vosteen K H
Arch Otorhinolaryngol. 1977 Aug 26;217(3):339-46. doi: 10.1007/BF00465551.
The source of EP and the production of the endolymph are often considered to be at the stria vascularis. However, the significance of Reissner's membrane in maintaining the ionic composition of the endolymph cannot be ruled out. We perfused the entire perilymphatic space of guinea pigs with paraffin oil to determine the effects on the endolymph and perilymph. After 1 and 2 h the endolymph was removed from the second turn and the ionic concentration of these samples was measured by flamephotometry. The results revealed no significant changes in Na+ and K+ concentration as compared to normal endolymph. EP was measured from the second turn under an equivalent experimental condition. During 1 h of oil perfusion, EP remained fairly constant. From these experiments we surmise that perilymph and Reissner's membrane do not influence the ionic composition of the endolymph and EP during 1 or 2 h of our experiments.
内淋巴电位（EP）的来源和内淋巴的产生通常被认为是在血管纹。然而，不能排除内耳膜在维持内淋巴离子组成方面的重要性。我们用石蜡油灌注豚鼠的整个外淋巴间隙，以确定其对内淋巴和外淋巴的影响。1小时和2小时后，从第二圈取出内淋巴，并用火焰光度法测量这些样本的离子浓度。结果显示，与正常内淋巴相比，钠（Na+）和钾（K+）浓度没有显著变化。在相同实验条件下，从第二圈测量EP。在灌注油1小时期间，EP保持相当稳定。从这些实验中我们推测，在我们实验的1或2小时内，外淋巴和内耳膜不会影响内淋巴的离子组成和EP。
