Williams G L, Campbell H, Davies K J
Br Med J. 1969 Jul 26;3(5664):212-5. doi: 10.1136/bmj.3.5664.212.
The incidence of impaired renal concentrating ability in pregnant women with asymptomatic significant bacteriuria is significantly less than previously reported when osmolality readings are performed on every urine specimen obtained during the 24 hours' deprivation of fluids. The concentrating defect is more considerable as pregnancy progresses. The lower the maximum urinary osmolality the more difficult is the treatment of the patient, and the higher the incidence of acute pyelonephritis.
当对在24小时禁水期间获取的每份尿液标本进行渗透压读数时,无症状菌尿症孕妇中肾浓缩能力受损的发生率显著低于先前报道。随着妊娠进展,浓缩缺陷更为明显。最大尿渗透压越低,患者治疗越困难,急性肾盂肾炎的发生率越高。