Henry L, Beverley J K
Br J Exp Pathol. 1969 Jun;50(3):230-8.
Myocardial lesions were found in 71 per cent of mice infected with a highly virulent strain of These were maximal in the terminal stages of the infection. They were also found in 79 per cent of mice infected with a non-fatal strain and these were maximal on the 17th day. Changes in the skeletal muscle were found in 44 per cent of mice infected with the less virulent strain. They were maximal on the 31st day. The histological appearances are described and discussed. Reports of myocarditis and myositis associated with infections in man are reviewed and diagnostic criteria are assessed. A plea is made for an increased awareness of these 2 manifestations in cases of toxoplasmosis.
在感染高毒力菌株的小鼠中，71%发现有心肌损伤。这些损伤在感染末期最为严重。在感染非致死性菌株的小鼠中，79%也发现有心肌损伤，且在第17天最为严重。在感染低毒力菌株的小鼠中，44%发现骨骼肌有变化，在第31天最为严重。描述并讨论了组织学表现。回顾了与人类弓形虫感染相关的心肌炎和肌炎的报告，并评估了诊断标准。呼吁在弓形虫病病例中提高对这两种表现的认识。
