Protein and isoamylase content of rat-submaxillary gland under the influence of alpha- and beta-sympathicolysis.

In order to study the function of adrenergic receptors in the submaxillary gland in vivo, rats were treated with the alpha-sympathicolytic, phentolamine (Regitin) and with the beta-sympathicolytic, propranolol (Dociton) and the protein, amylase, and isoamylase content of their submaxillary glands were investigated. The protein concentration rises after 3 weeks of alpha- as well as combined alpha- and beta-sympathicolysis while the amylase concentrations remain, on the whole, unchanged. The pharmacologically induced secretory inhibitions are being discussed in connection with the generally accepted receptor functions.