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一种新型抗抑郁药布替林:血浆水平与临床反应。

A new antidepressant butriptyline: plasma levels and clinical response.

作者信息

Burrows G D, Norman T R, Maguire K P, Rubinstein G, Scoggins B A, Davies B

出版信息

Med J Aust. 1977 Oct 29;2(18):604-6. doi: 10.5694/j.1326-5377.1977.tb107663.x.

DOI:10.5694/j.1326-5377.1977.tb107663.x
PMID:579645
Abstract

Ten patients who suffered from a primary depressive illness were treated with a new antidepressant drug butriptyline (150 mg/day). Six of the patients showed marked clinical improvement, as judged by depression rating scores, at the end of 22 days of treatment. No simple relationship was found between clinical response and plasma butriptyline concentration. Butriptyline is an effective antidepressant agent, well tolerated and with few side effects.

摘要

10名患有原发性抑郁症的患者接受了一种新型抗抑郁药物布替林(150毫克/天)的治疗。根据抑郁评分,在治疗22天后,其中6名患者显示出明显的临床改善。临床反应与血浆布替林浓度之间未发现简单的关系。布替林是一种有效的抗抑郁药,耐受性良好,副作用较少。

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A new antidepressant butriptyline: plasma levels and clinical response.一种新型抗抑郁药布替林:血浆水平与临床反应。
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