Kokron O
Osterr Z Onkol. 1977 Dec 19;4(4):82-5.
From 1970 to 1976, 268 patients with pleural effusions underwent local therapy with the polyenzyme preparation Wobemugos; 235 patients were evaluable regarding the effectiveness of this therapy. In 115 of the cases, the primary tumour was carcinoma of the bronchus, in 86, carcinoma of the breast, in 9, mesothelioma and carcinoma of the ovary each, and in 16, other malignancies. There was a total remission of pleural effusions in 42% of the cases, a partial one in 41%, and no effect in 17%. In spite of the relatively large number of patients, some difficulties in interpreting the present results still remain and will be discussed in this paper.
1970年至1976年期间，268例胸腔积液患者接受了多酶制剂沃贝酶素的局部治疗；235例患者可评估该治疗的有效性。其中115例原发性肿瘤为支气管癌，86例为乳腺癌，9例为间皮瘤，9例为卵巢癌，16例为其他恶性肿瘤。42%的病例胸腔积液完全缓解，41%部分缓解，17%无效。尽管患者数量相对较多，但在解释目前的结果时仍存在一些困难，本文将对此进行讨论。
