Kokron O, Titscher R, Micksche M, Cerni C, Wrba H
Osterr Z Onkol. 1977 Nov 15;4(5-6):103-6.
Clinical experiences obtained until now in the treatment of 47 patients with small cell carcinoma of the bronchus with Holoxan are reported. Special emphasis is laid to the results of a prospective randomized study; two groups of patients, one of them undergoing Holoxan therapy, the other receiving symptomatic treatment, have been investigated in respect of relationship between tumour remission, quality of life and survival time.
报告了迄今为止用环磷酰胺治疗47例支气管小细胞癌患者所获得的临床经验。特别强调了一项前瞻性随机研究的结果;对两组患者进行了调查,一组接受环磷酰胺治疗,另一组接受对症治疗,调查内容包括肿瘤缓解、生活质量和生存时间之间的关系。