Schmidt C G, Becher R
Dtsch Med Wochenschr. 1979 Jun 15;104(24):872-5. doi: 10.1055/s-0028-1104005.
15 patients with metastasing melanoblastoma of stage III and IV were treated with a combination of cis-platinum (II)-diamminodichloride and ifosfamide. In 3 cases complete remission occurred, in 5 partial remission with tumour regression of more than 50%. The response rate is around 50% at present. Two cases showed no change after 6 months of chemotherapy.
15例Ⅲ期和Ⅳ期转移性黑色素瘤患者接受了顺铂(II)-二氨二氯铂和异环磷酰胺联合治疗。3例完全缓解,5例部分缓解,肿瘤消退超过50%。目前缓解率约为50%。2例患者化疗6个月后病情无变化。