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Enzymic control of irreversible binding of metabolically activated benzo(a)pyrene in perfused rat liver by monooxygenase activity.

作者信息

Kahl G F, Klaus E, Jonen H G, Kahl R

出版信息

Arch Toxicol. 1977 Dec 30;39(1-2):149-58. doi: 10.1007/BF00343282.

DOI:10.1007/BF00343282
PMID:579978
Abstract
摘要

相似文献

1
Enzymic control of irreversible binding of metabolically activated benzo(a)pyrene in perfused rat liver by monooxygenase activity.通过单加氧酶活性对灌注大鼠肝脏中代谢活化苯并(a)芘不可逆结合的酶促控制。
Arch Toxicol. 1977 Dec 30;39(1-2):149-58. doi: 10.1007/BF00343282.
2
Aryl hydrocarbon (benzo[a]pyrene) hydroxylase development in rat mammary tissue.
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Modulation of the in vivo covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA by selective induction of microsomal and nuclear aryl hydrocarbon hydroxylase activity.通过选择性诱导微粒体和细胞核芳烃羟化酶活性来调节致癌物苯并(a)芘与大鼠肝脏DNA的体内共价结合。
Arch Toxicol Suppl. 1979(2):285-8. doi: 10.1007/978-3-642-67265-1_25.
4
Increase of liver microsomal benzo(a)pyrene monooxygenase activity by subsequent glucuronidation.
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5
Age- and sex-dependent induction of liver microsomal benzo[a]pyrene hydroxylase activity in rats treated with pregnenolone-16 alpha-carbonitrile (PCN).孕烯醇酮-16α-腈(PCN)处理的大鼠中肝微粒体苯并[a]芘羟化酶活性的年龄和性别依赖性诱导。
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Influence of inducers and inhibitors of mixed-function oxidasts on benzo(a)pyrene binding to the DNA of rat liver nuclei.混合功能氧化酶诱导剂和抑制剂对苯并(a)芘与大鼠肝细胞核DNA结合的影响。
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7
Induction, modification and inhibition of rat liver microsomal benzo(a)pyrene hydroxylase; correlation with the S-9-mediated mutagenicity of benzo(a)pyrene.大鼠肝脏微粒体苯并(a)芘羟化酶的诱导、修饰及抑制;与苯并(a)芘的S-9介导致突变性的相关性
Biochem Biophys Res Commun. 1978 Dec 14;85(3):1007-16. doi: 10.1016/0006-291x(78)90643-5.
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High benzo[a]pyrene hydroxylase activity in the marine fish Stenotomus versicolor.海洋鱼类多锯鲈中苯并[a]芘羟化酶活性较高。
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Aryl hydrocarbon (benzo[a]pyrene) hydroxylase in rat mammary tissue during pregnancy and lactation.
Can J Physiol Pharmacol. 1979 Jan;57(1):112-7. doi: 10.1139/y79-017.
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Correlation between the kinetic parameters of the microsomal benzo(a)pyrene hydroxylase and the mutagenicity of benzo(a)pyrene in vitro [proceedings].微粒体苯并(a)芘羟化酶动力学参数与苯并(a)芘体外诱变性的相关性[会议论文集]
Arch Int Physiol Biochim. 1978 May;86(2):447-8.

引用本文的文献

1
Binding of benzo(a)pyrene metabolites to cellular DNA in perfused rat lungs.苯并(a)芘代谢产物与灌注大鼠肺细胞DNA的结合。
Naunyn Schmiedebergs Arch Pharmacol. 1978 Jul;303(3):303-7. doi: 10.1007/BF00498059.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The dominant role of the liver in plasma protein synthesis; a direct study of the isolated perfused rat liver with the aid of lysine-epsilon-C14.肝脏在血浆蛋白合成中的主导作用;借助赖氨酸-ε-C14对离体灌注大鼠肝脏进行的直接研究。
J Exp Med. 1951 Nov;94(5):431-53. doi: 10.1084/jem.94.5.431.
3
THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES.肝微粒体的一氧化碳结合色素。II. 增溶、纯化及性质
J Biol Chem. 1964 Jul;239:2379-85.
4
EVIDENCE FOR THE BINDING OF POLYNUCLEAR AROMATIC HYDROCARBONS TO THE NUCLEIC ACIDS OF MOUSE SKIN: RELATION BETWEEN CARCINOGENIC POWER OF HYDROCARBONS AND THEIR BINDING TO DEOXYRIBONUCLEIC ACID.多环芳烃与小鼠皮肤核酸结合的证据:烃类致癌能力与其与脱氧核糖核酸结合之间的关系。
Nature. 1964 May 23;202:781-4. doi: 10.1038/202781a0.
5
METABOLIC REGULATORY CIRCUITS AND CARCINOGENESIS.代谢调节回路与致癌作用
Cancer Res. 1963 Nov;23:1694-700.
6
Studies of electron transport enzymes. III. Cytochrome b5 of pig liver mitochondria.电子传递酶的研究。III. 猪肝线粒体的细胞色素b5
J Biol Chem. 1959 Jul;234(7):1867-73.
7
The deoxyribonucleic acid content of the rat cell nucleus and its use in expressing the results of tissue analysis, with particular reference to the composition of liver tissue.大鼠细胞核的脱氧核糖核酸含量及其在表达组织分析结果中的应用,特别涉及肝组织的组成。
Biochem J. 1953 Feb;53(3):460-74. doi: 10.1042/bj0530460.
8
Epoxides as microsomal metabolites of polycyclic hydrocarbons.环氧化物作为多环烃的微粒体代谢产物。
FEBS Lett. 1971 Oct 15;18(1):76-80. doi: 10.1016/0014-5793(71)80411-8.
9
The interaction of 7,12-dimethylbenz(a)anthracene with cells sensitive and resistant to toxicity induced by this carcinogen.7,12-二甲基苯并(a)蒽与对该致癌物诱导的毒性敏感和耐药的细胞之间的相互作用。
Cancer Res. 1967 May;27(5):890-7.
10
Gluconeogenesis in the perfused rat liver.灌注大鼠肝脏中的糖异生作用。
Biochem J. 1966 Nov;101(2):284-92. doi: 10.1042/bj1010284.