Stürzebecher E, Wernecke K D, Wagner H, Gerhardt H J
Arch Otorhinolaryngol. 1977 Dec 20;218(1-2):19-25.
Many authors consider the nature of the slow acoustically evoked potentials to be partly a specific one. Therefore the AEP-time behavior probably contains more information about the functional state of the acoustical channel than it is got by the usual measurement of only 3 values (N1P2-amplitude, 2 latencies). A test of this hypothesis is possible with a multivariate mathematical procedure, which involves the whole AEP-time behavior. We are using the multivariate variance- and discriminant analysis. For the application of this statistical method random samples of patients with certain otologic diseases are needed. To avoid mistakes in grouping these samples some preliminary investigations had been necessary: This paper reports the results of multivariate investigations concerning age differences of the AEP in normal hearing adults. By means of the multivariate variance analysis the AEP of 3 age groups were examined (group 1: 15--34 years, group 2: 35--44 years, group 3: 45--60 years). At 1000 Hz as well as at 400 Hz significant differences between the group averages were found, which were not detectable by the usual N1P2-amplitude measurement. Furthermore with the discriminant analysis it is possible to perform a relatively reliable differentiation between the individual AEP of the age groups 1 and 3.
许多作者认为,慢听性诱发电位的性质部分是特异性的。因此,听觉诱发电位(AEP)的时间行为可能比仅通过通常测量3个值(N1P2振幅、2个潜伏期)获得的信息,包含更多关于听觉通道功能状态的信息。使用涉及整个AEP时间行为的多元数学程序,可以对这一假设进行检验。我们正在使用多元方差分析和判别分析。为了应用这种统计方法,需要患有某些耳科疾病患者的随机样本。为了避免在对这些样本进行分组时出现错误,一些初步研究是必要的:本文报告了关于正常听力成年人AEP年龄差异的多元研究结果。通过多元方差分析,对3个年龄组的AEP进行了检查(第1组:15 - 34岁,第2组:35 - 44岁,第3组:45 - 60岁)。在1000Hz以及400Hz时,发现组平均值之间存在显著差异,而这是通过通常的N1P2振幅测量无法检测到的。此外,通过判别分析,可以在第1组和第3组的个体AEP之间进行相对可靠的区分。