Hamada H, Izumi K, Hirabayashi K, Iko T, Inomata K, Tokito S
No Shinkei Geka. 1978 Jan;6(1):97-103.
A relatively rare case of malignant lymphoma of the brain was reported. A 64-year-old male was admitted to our hospital, October 2, 1976, complaining of right hemiparesis and expressive aphasia. Neurological and radiological examinations revealed a huge space-occupying lesion in the left frontoparietal region. An external decompressive surgery and biopsy were performed. The excised specimens was diagnosed as malignant lymphoma (lymphosarcoma type) histologically. Radiation (5000 rad of 60Co) and chemotherapy with anticancer drugs were carried out after the operation. The patient, however, died at seven months after the onset. On necropsy the tumor was infiltrated extensively in the left frontal, parietal, temporal and occipital lobes, but extended not to the thalamus, basal ganglia and ventricular system. This case was suggested primary malignant lymphoma of the brain, according to the physical and radiological examinations of the whole body, although the autopsy was performed only about the brain. The nomenclature, clinicopathological and immunological problems of malignant lymphomas of the nervous system were also discussed, reviewing the previously reported cases.
报告了1例相对罕见的脑恶性淋巴瘤病例。1976年10月2日，一名64岁男性因右侧偏瘫和表达性失语入住我院。神经学和放射学检查发现左额顶叶区有一个巨大占位性病变。进行了去骨瓣减压手术和活检。切除标本经组织学诊断为恶性淋巴瘤（淋巴肉瘤型）。术后进行了放疗（60钴5000拉德）和抗癌药物化疗。然而，患者在发病七个月后死亡。尸检发现肿瘤广泛浸润左额叶、顶叶、颞叶和枕叶，但未累及丘脑、基底神经节和脑室系统。尽管仅对脑部进行了尸检，但根据全身的体格检查和放射学检查，该病例提示为原发性脑恶性淋巴瘤。还回顾了先前报道的病例，讨论了神经系统恶性淋巴瘤的命名、临床病理和免疫学问题。
