斐济八角枫提取物（ICIG-EORTC 1131、1186和1207）对小鼠淋巴瘤的抑瘤作用。
Oncostatic effects of Alangium vitiense extracts (ICIG-EORTC 1131, 1186 and 1207) on lymphoid murine tumors.
作者信息
Mathé G, Hayat M, Chenu E, Husson H P, Thevenet T, Kan C, Potier P
出版信息
Cancer Res. 1978 May;38(5):1465-7.
PMID:580415
Abstract
A total alkaloid and two purified alkaloid extracts of Alangium vitiense were found to be oncostatic for L1210 leukemia; the total alkaloid exerted a noticeable activity, and the purified extracts exerted a borderline activity. These two purified extracts are noticeably oncostatic for two other lymphoid neoplasias in mice, P388 leukemia and Gardner lymphosarcoma. These compounds are not active on Warner myelomonocytic leukemia WEH13 or on B16 melanoma.
摘要
发现维蒂氏八角枫的一种总生物碱提取物和两种纯化的生物碱提取物对L1210白血病具有抑癌作用；总生物碱表现出显著活性，而纯化提取物表现出临界活性。这两种纯化提取物对小鼠的另外两种淋巴样肿瘤——P388白血病和加德纳淋巴肉瘤具有明显的抑癌作用。这些化合物对沃纳骨髓单核细胞白血病WEH13或B16黑色素瘤没有活性。
Zotero 插件