Eitschberger E, Gammert C, Pesch H H, Henschke F
Arch Otorhinolaryngol. 1978 Mar 3;220(1-2):141-8.
In 26 cases allogenetic human dura mater, conserved in CialitTM 1:5000, was used to close perforations of the eardrum instead of commonly used autogenetic fascia of the temporal muscle. In preceding animal studies, it had been found that "Cialit dura" acts as guideline and stimulates the development of new host connective tissue. In 25 human ear drums the perforations healed up without any problems. The healing process took times of up to 8 weeks. Only in one case a new perforation was found. The moderate flexibility of "Cialit dura" proved as a special advantage during the surgery procedure. Human dura is easily to acquire and its conservation is simple and cheep. Therefore it can serve as a grafting material for tympanoplasty available at any time and in any size. For very large transplants and a lack of postoperative treatment the prolonged healing period could be of some disadvantage. For normal sized transplants, however, there seems not to be a difference in healing time between the commonly used fascia and the "Cialit dura".
在26例手术中，使用保存在1:5000西阿利特（CialitTM）中的同种异体人硬脑膜来封闭鼓膜穿孔，而非常用的颞肌自体筋膜。在之前的动物研究中，已发现“西阿利特硬脑膜”起到引导作用，并刺激新的宿主结缔组织生长。在25例人鼓膜中，穿孔顺利愈合。愈合过程耗时长达8周。仅1例出现新的穿孔。“西阿利特硬脑膜”适度的柔韧性在手术过程中被证明是一项特殊优势。人硬脑膜易于获取，保存简单且成本低廉。因此，它可随时作为鼓膜成形术的移植材料，且尺寸任意。对于非常大的移植以及缺乏术后治疗的情况，愈合期延长可能存在一些不利之处。然而，对于正常尺寸的移植，常用的筋膜与“西阿利特硬脑膜”在愈合时间上似乎并无差异。
