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狒狒(阿拉伯狒狒)淋巴瘤的病毒学研究:泡沫病毒的分离与鉴定

Virological studies of baboon (Papio hamadryas) lymphoma: isolation and characterization of foamyviruses.

作者信息

Rabin H, Neubauer R H, Woodside N J, Cicmanec J L, Wallen W C, Lapin B A, Agrba V A, Yakoleva L A, Chuvirov G N

出版信息

J Med Primatol. 1976;5(1):13-22. doi: 10.1159/000459903.

Abstract

In accordance with a memorandum of understanding in cancer research between scientists in the USSR and the USA, virological studies were performed on two baboons from the Russian colony at the Institute of Experimental Pathology and Therapy at Sukhumi where several cases of leukemia have been observed over the past few years. Foamyvirus isolations were made from lymphoid cells of both of these monkeys, one of which had a confirmed case of lymphoma. The isolates were similar to each other serologically and morphologically, possessed characteristics typical of foamyviruses, and cross-reacted to a low level with antibody to simian foamyvirus type 1.

摘要

根据苏联和美国科学家之间关于癌症研究的一项谅解备忘录,对来自苏呼米实验病理学与治疗研究所俄罗斯种群的两只狒狒进行了病毒学研究,在过去几年里该研究所观察到了几例白血病病例。从这两只猴子的淋巴细胞中分离出了泡沫病毒,其中一只确诊患有淋巴瘤。这些分离株在血清学和形态学上彼此相似,具有泡沫病毒的典型特征,并与1型猿泡沫病毒抗体发生低水平交叉反应。

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