Horner G, Lehmann V
Arch Gynakol. 1978 May 12;225(2):161-9. doi: 10.1007/BF00670851.
The influence of estradiolbenzoate, hydroprogesteroncapronate and pregnancy on the mechanical reaction of the directly and indirectly stimulated nerve-diaphragm preparation has been the subject of this investigation. Rats were ovario-ectomized and the hormone preparations were injected subcutaneously. After a lapse of 9 days the test preparation was made. 1. Estrogen and the estrogen-gestagen combination have a similar effect on the isometric contraction of the transversely striated muscle. The times of rising and relaxation were prolonged after indirect and direct stimulation. The contraction amplitude had not altered compared to the control group. 2. Gestagens and the hormone situation of pregnancy entail, independent of the kind of stimulation, a decrease of the tension progress and the speed of the tension increase. The gestagen-treated animals underwent a shortened contraction process. These findings enable us to comment on the different efficiencies of women during various cycle phases and during pregnancy.
苯甲酸雌二醇、己酸羟孕酮和妊娠对直接和间接刺激的神经 - 膈肌标本机械反应的影响是本研究的主题。将大鼠卵巢切除，并皮下注射激素制剂。9天后制作测试标本。1. 雌激素和雌激素 - 孕激素组合对横纹肌的等长收缩有相似的作用。间接和直接刺激后，上升和松弛时间延长。与对照组相比，收缩幅度没有改变。2. 孕激素和妊娠时的激素状态，与刺激类型无关，会导致张力进展和张力增加速度降低。接受孕激素治疗的动物收缩过程缩短。这些发现使我们能够对女性在不同周期阶段和怀孕期间的不同效率进行评论。
