[Isolated neoplastic foci in the central nervous system in generalized non-Hodgkin-lymphomas. A prospective pathomorphological study (author's transl)].

A comprehensive post-mortem investigation of the central nervous system (CNS) in 103 patients with malignant non-Hodgkin-lymphomas was performed. Neoplastic foci were revealed in the CNS in 21 cases. Five of them were visible at gross examination. Strong evidence exists that the incidence of the CNS-involvement is correlated with the lymphoma-type. Our cases were classified according to the Kiel-classification (Lennert 1975). The findings suggest that CNS-infiltrations are rather common in lymphoblastomas and immunocytomas whereas they seldom occur in plasmocytomas.