Yacoub M H, Kothari M, Keeling D, Patterson M, Ross D N
Thorax. 1969 May;24(3):283-6. doi: 10.1136/thx.24.3.283.
Red cell survival was studied in 21 patients following homograft replacement of the aortic valve. Autologous cells labelled with Cr were used. The T½ Cr varied between 24 and 34 days, with only one patient below the normal limit of normal variations. The absence of haemolysis was confirmed by other haematological studies, including estimation of reticulocytes, serum lactic dehydrogenase, and urinary haemosiderin. Haptoglobin levels were low in most of the patients studied. In contrast to prosthetic valves there was no haemolysis in patients with regurgitation around or through the homograft valve.
对21例接受主动脉瓣同种移植置换术的患者进行了红细胞存活研究。使用用铬标记的自体细胞。铬的半衰期在24至34天之间变化，只有1例患者低于正常变异的正常下限。包括网织红细胞计数、血清乳酸脱氢酶和尿含铁血黄素测定在内的其他血液学研究证实无溶血现象。在所研究的大多数患者中，触珠蛋白水平较低。与人工瓣膜不同，同种移植瓣膜周围或通过同种移植瓣膜反流的患者没有溶血现象。
