对泛影葡胺的肺部反应。

Thorax. 1969 May;24(3):353-8. doi: 10.1136/thx.24.3.353.

Hytrast, a new bronchographic medium of high iodine content, provides excellent radiographic contrast. A number of clinical, pathological, and experimental studies have revealed inflammatory changes after pulmonary retention of Hytrast. Examination of 43 unselected pneumonectomy specimens after Hytrast bronchography revealed typical crystals in 15 instances. The pulmonary reaction included macrophage and foreign body giant cell accumulation, neutrophil leucocyte exudation, and fibrosis within terminal bronchioles and alveoli. It was concluded that these changes were associated with Hytrast retention.

海特拉斯特（Hytrast）是一种新型的高碘含量支气管造影剂，能提供出色的放射造影效果。多项临床、病理和实验研究表明，海特拉斯特滞留于肺部后会引发炎症变化。对43例未经筛选的肺切除标本进行海特拉斯特支气管造影检查后发现，有15例出现了典型晶体。肺部反应包括巨噬细胞和异物巨细胞聚集、中性粒细胞渗出，以及终末细支气管和肺泡内的纤维化。得出的结论是，这些变化与海特拉斯特的滞留有关。