Saad A A, El-Zoghby S M, Farag H F, el-Sewedy S M, Girgis L H, Moghazy M
Acta Vitaminol Enzymol. 1977;31(6):183-6.
beta-Glucuronidase activity is elevated in the urine of patients with bilharziasis hematobium. In the present study the enzyme level was estimated in whole urinary bladder tissue homogenates of mice experimentally infected with Schistosoma mansoni. In the infected mice the enzyme activity is significantly higher than in the controls. The effect of the schistosomicidal drug hycanthone was also evaluated. Treatment with the drug did not affect the level of the enzyme activity in the infected mice; it induced an increase in the enzyme activity of the controls.
埃及血吸虫病患者尿液中的β-葡萄糖醛酸酶活性升高。在本研究中,对实验感染曼氏血吸虫的小鼠全膀胱组织匀浆中的该酶水平进行了测定。在感染小鼠中,该酶活性显著高于对照组。还评估了杀血吸虫药物海恩酮的作用。用该药物治疗对感染小鼠的酶活性水平没有影响;它导致对照组的酶活性增加。