Avery T L
Science. 1969 Apr 25;164(3878):423-4. doi: 10.1126/science.164.3878.423.
Pituitaries of female mice in anestrus resulting from colony housing were characterized by a 58.0-percent (acidophil content. Subsequent exposure to restrained male mice for one and two nights failed to evoke significant acidophilic degranulation and resulted in pituitary acidophil values of 57.4 and 55.1 percent respectively. Exposure to released males on the third night produced marked acidophilic degranulation resulting in a significant decline in pituitary acidophils to 38.0 percent. These findings support the view that female pheromone suppresses and male pheromone favors the secretion of follicle-stimulating hormone and indicate that luteotrophic hormone is secreted at its assigned time in the sequence of cyclic ovarian events initiated by the secretion of follicle-stimulating hormone.
群居导致处于静止期的雌性小鼠垂体的嗜酸性细胞含量为58.0%。随后，让其与受限制的雄性小鼠接触一晚和两晚，均未引起明显的嗜酸性细胞脱粒，垂体嗜酸性细胞值分别为57.4%和55.1%。在第三晚与自由活动的雄性小鼠接触后，出现了明显的嗜酸性细胞脱粒，导致垂体嗜酸性细胞显著减少至38.0%。这些发现支持了以下观点：雌性信息素抑制而雄性信息素促进促卵泡激素的分泌，并表明促黄体激素在由促卵泡激素分泌引发的周期性卵巢活动序列中按其指定时间分泌。
