Carlson B R, Weinberg A G
Arch Pathol Lab Med. 1978 Nov;102(11):596-9.
An infant with cerebrohepatorenal syndrome of Zellweger had extensive hepatic giant cell transformation at 6 1/2 weeks of age. At 16 weeks the liver showed early cirrhosis and rare giant cells. Changes previously described have ranged from no abnormality in the neonate to cirrhosis at 20 weeks of age and indicate progression of liver disease in affected patients.
一名患有泽尔韦格脑肝肾综合征的婴儿在6.5周龄时出现广泛的肝脏巨细胞转化。16周时，肝脏显示早期肝硬化且巨细胞罕见。先前描述的变化范围从新生儿无异常到20周龄时出现肝硬化，这表明受影响患者的肝脏疾病在进展。
