Macgillivray J B
J Clin Pathol. 1969 May;22(3):340-7. doi: 10.1136/jcp.22.3.340.
The incidence of breast cancer complicating chronic mastitis with epitheliosis has been reported to be as high as 45% and as low as 6%. At least part of this discrepancy appears to be due to difficulty in distinguishing between benign and malignant intraduct epithelial proliferation.A small series is presented here in which the incidence of invasive cancer after local excision of breast tissue showing chronic mastitis with epitheliosis was nil. It is concluded that it is necessary to follow up larger series of cases longer before it can be said that severe epitheliosis and borderline lesions should in all cases be treated by anything more radical than local excision.
据报道,慢性乳腺炎合并上皮增生并发乳腺癌的发生率高达45%,低至6%。这种差异至少部分似乎是由于难以区分良性和恶性导管内上皮增生。本文报告了一小系列病例,其中显示慢性乳腺炎合并上皮增生的乳腺组织局部切除术后浸润性癌的发生率为零。得出的结论是,在能够说所有严重上皮增生和临界病变都应采用比局部切除更激进的治疗方法之前,有必要对更多系列的病例进行更长时间的随访。