Osadchiĭ L I
Fiziol Zh SSSR Im I M Sechenova. 1978 Nov;64(11):1592-1600.
The orthostatic test (OT) induced regular constrictor responses of the resistance vessels and less regular those of the capacitance vessels under conditions of extracorporeal circulation (by passing the left ventricle) in anesthetized cats. Responses of the resistance vessels were eliminated by ganglionic blockade, while blood pooling rised only in half of experiments under these conditions. In case of natural circulation, the ganglionic blockade entailed an obvious initial hypotension followed by lowering of compensatory elevation of arterial pressure (AP) while responses of the cardiac output to OT remained unchanged. By the method of extracorporeal circulation combined with the "working" heart significant lowering of the cardiac output to OT was achieved; this response was accompanied by constrictor responses of the resistance vessels. Compensatory responses of AP reveal themselves mainly by the vascular component of the systemic reaction.
在麻醉猫体外循环(绕过左心室)条件下,直立试验(OT)引起阻力血管有规律的收缩反应,而容量血管的反应则不太规律。神经节阻断可消除阻力血管的反应,而在这些条件下,只有一半的实验出现血液淤积增加。在自然循环情况下,神经节阻断会导致明显的初始低血压,随后动脉压(AP)的代偿性升高降低,而心输出量对OT的反应保持不变。通过体外循环结合“工作”心脏的方法,可实现心输出量对OT的显著降低;这种反应伴有阻力血管的收缩反应。AP的代偿反应主要通过全身反应的血管成分表现出来。