Nochimson D J, Petrie R H
Am J Obstet Gynecol. 1979 Feb 15;133(4):449-51.
Twenty hypertensive gravid women who had their pregnancies terminated for maternal indications because of the severity of pre-eclampsia or chronic hypertension were studied. They were treated at 27 to 33 weeks of gestation with 48 hours of betamethasone therapy prior to delivery. There was one antepartum fetal death, and it is believed that this death was preventable. There was an incidence of respiratory distress syndrome (RDS) of 23% with two neonatal deaths secondary to RDS, for a treated neonatal survival of 85.7%. All losses were from mothers with pre-eclampsia. Pregnancy-related hypertension is not thought to be an absolute contraindication to glucocorticoid therapy for the induction of pulmonary maturity.
对20名因重度子痫前期或慢性高血压而因母体指征终止妊娠的高血压孕妇进行了研究。她们在妊娠27至33周时，于分娩前接受了48小时的倍他米松治疗。有1例产前胎儿死亡，据信这一死亡是可以避免的。呼吸窘迫综合征（RDS）的发生率为23%，有2例新生儿因RDS死亡，治疗后的新生儿存活率为85.7%。所有死亡均发生在子痫前期的母亲中。妊娠相关高血压不被认为是糖皮质激素治疗诱导肺成熟的绝对禁忌证。
