Batra S, Bengtsson L P
Lancet. 1976 May 29;1(7970):1164-5. doi: 10.1016/s0140-6736(76)91547-6.
It is proposed that uterine hypoxia, beginning initially with the uterine contractions in late pregnancy, leads to the increased formation of free fatty acids. The liberated fatty acids are then used to form prostaglandins and they can also act on mitochondria to release calcium. The released calcium can directly activate contractile proteins and/or can further stimulate phospholipase A (active at neutral pH) and thereby reinforce the progressive production of prostaglandins.
有人提出，子宫缺氧最初始于妊娠晚期的子宫收缩，会导致游离脂肪酸生成增加。释放出的脂肪酸随后用于形成前列腺素，它们还可作用于线粒体以释放钙。释放出的钙可直接激活收缩蛋白和/或进一步刺激磷脂酶A（在中性pH下具有活性），从而加强前列腺素的逐步产生。
