Ahmadiar N, Ruiz-Torres A
Arzneimittelforschung. 1979;29(2):284-6.
Using the method of the perfused small intestine preparation in situ, the influence of triiodothyronine on the absorption was investigated. The absorptions of L-proline and digitoxin were disturbed by the thyroid hormone in different ways, in contrast to chloramphenicol, where it is unaltered. The effects of triiodothyronine on the absorption of these substances are dose dependently different. Obviously the thyroid hormone can influence the absorption of proline and digitoxin in both ways, increase or decrease. The behaviour of digitoxin different from that of chloramphenicol points to this drug making use of active mechanisms concerned in the absorption.
采用原位灌注小肠制备方法，研究了三碘甲状腺原氨酸对吸收的影响。与氯霉素吸收不受影响不同，甲状腺激素以不同方式干扰了L-脯氨酸和地高辛的吸收。三碘甲状腺原氨酸对这些物质吸收的影响存在剂量依赖性差异。显然，甲状腺激素可以通过增加或减少两种方式影响脯氨酸和地高辛的吸收。地高辛与氯霉素的表现不同，表明该药物利用了吸收过程中的主动机制。
