Analytical-physical profile of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent.
作者信息
Zalipsky J J, Won C M, Patel D M
出版信息
Arzneimittelforschung. 1978;28(8a):1441-7.
PMID:582535
Abstract
The structure elucidation, physical and chemical parameters and hydrolysis kinetics of 1-(2,6-dimethylphenyl)-3-methylamidinourea hydrochloride (WHR-1142 A, lidamidine hydrochloride), a novel antidiarrheal agent, were determined. The stability of the substance in aqueous solution (pH 1-13) was studied at 50 degrees, 65 degrees and 80 degrees C.
摘要
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