Straube E, Heimann H
Arzneimittelforschung. 1978;28(9):1485-9.
The psychophysiological and psychopathological implications are discussed for the finding that absence of electrodermal orienting response to acoustic stimuli was observed among 40% of the schizophrenic patients in two samples. It was found that withdrawal symptomatology and thought disturbance frequently appear among those patients without orienting response. Examples from previous studies are presented which verify deficient or excessive responses of schizophrenics in other physiological variables. It is suggested that extreme psychobiological primary characteristics of schizophrencis be taken into account in psychopharmacological therapy.
针对在两个样本中40%的精神分裂症患者身上观察到对听觉刺激缺乏皮肤电定向反应这一发现，讨论了其心理生理和精神病理学意义。研究发现，在那些没有定向反应的患者中，戒断症状和思维紊乱经常出现。文中列举了先前研究的例子，这些例子证实了精神分裂症患者在其他生理变量方面存在反应不足或过度的情况。建议在精神药物治疗中考虑精神分裂症极端的心理生物学主要特征。
