Scheller S, Luciak M, Tustanowski J, Koziol M, Obuszko Z, Kurylo B
Arzneimittelforschung. 1978;28(9):1594-5.
Mice were given i.v. injections of water solutions of ethanol extract of propolis (EEP) over a varying period of time. Some of the animals were sacrificed immediately following the last injection and some within 2--4 weeks after the last injections. Internal organ samples were taken and underwent a microscopic examination. Insignificant pathological changes in the liver were observed. These changes were transient and regressed within 2--4 weeks after the application of EEP.
在不同时间段内给小鼠静脉注射蜂胶乙醇提取物(EEP)的水溶液。一些动物在最后一次注射后立即处死,另一些在最后一次注射后的2至4周内处死。采集内部器官样本并进行显微镜检查。观察到肝脏有不明显的病理变化。这些变化是短暂的,在应用EEP后的2至4周内消退。