激肽释放酶对缓激肽的拮抗作用。
Antagonistic effect of kallikrein against bradykinin.
作者信息
Ercan Z S, Türker R K, Torunoglu M
出版信息
Arzneimittelforschung. 1978;28(10):1712-4.
PMID:582675
Abstract
The interaction of kallikrein with bradykinin, eledoisin and histamine was studied on the perfused hindquarters of the cat and isolated cat jejunum. The vasodilation induced by bradykinin, but not by eledoisin and histamine, was found to be inhibited by kallikrein. Kallikrein also inhibited the myotropic effect of bradykinin on the isolated cat jejunum. The possible mechanisms of the inhibitory action of kallikrein against bradykinin were discussed.
摘要
在猫的灌注后肢和离体猫空肠上研究了激肽释放酶与缓激肽、eledoisin和组胺的相互作用。发现激肽释放酶可抑制缓激肽诱导的血管舒张，但对eledoisin和组胺诱导的血管舒张无此作用。激肽释放酶还抑制缓激肽对离体猫空肠的肌动效应。并对激肽释放酶对缓激肽的抑制作用的可能机制进行了讨论。
相似文献
1
Antagonistic effect of kallikrein against bradykinin.激肽释放酶对缓激肽的拮抗作用。
Arzneimittelforschung. 1978;28(10):1712-4.
2
3
A comparison in conscious and anaesthetized dogs of the effect on blood pressure of bradykinin, kallidin, eledoisin and kallikrein.
Eur J Pharmacol. 1967 Nov;2(2):83-7. doi: 10.1016/0014-2999(67)90029-5.
4
5
Inhibition of bradykinin- and kallikrein-induced cerebral arteriolar dilation by a specific bradykinin antagonist.一种特异性缓激肽拮抗剂对缓激肽和激肽释放酶诱导的脑小动脉扩张的抑制作用。
Stroke. 1987 Jul-Aug;18(4):792-5. doi: 10.1161/01.str.18.4.792.
6
The actions of some vasoactive polypeptides and their antagonists on the anococcygeus muscle.某些血管活性多肽及其拮抗剂对肛尾肌的作用。
Br J Pharmacol. 1978 Feb;62(2):267-74. doi: 10.1111/j.1476-5381.1978.tb08455.x.
7
[A direct central action of bradykinin (1)].[缓激肽的直接中枢作用(1)]
Shikwa Gakuho. 1984 Apr;84(4):677-86.
8
Potentiation of insulin stimulation of hexose transport by kallikrein and bradykinin in isolated rat adipocytes.激肽释放酶和缓激肽对离体大鼠脂肪细胞中胰岛素刺激己糖转运的增强作用。
Mol Cell Endocrinol. 1987 Apr;50(3):183-91. doi: 10.1016/0303-7207(87)90016-5.
9
The action of iodinated kallikrein on the rat uterus.碘化激肽释放酶对大鼠子宫的作用。
Agents Actions Suppl. 1992;36:265-70.
10
[ON THE EFFECT OF BRADYKININ, KALLIDIN AND ELEDOISIN ON THE CAT AND RABBIT INTESTINE IN SITU].[关于缓激肽、胰激肽和伊索辛对猫和兔原位肠管的作用]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1965 Apr 29;250:459-68. doi: 10.1007/BF00246896.
Zotero 插件