胸腺DNA对L1210肿瘤生长的抑制作用。
Inhibition of L1210 tumor growth by thymus DNA.
作者信息
Glick J L, Goldberg A R
出版信息
Science. 1965 Aug 27;149(3687):997-8. doi: 10.1126/science.149.3687.997.
PMID:5827348
Abstract
Growth of L1210 leukemia cells which had been previously incubated with thymus DNA was inhibited. Leukemia-cell DNA did not affect tumor growth under similar conditions. Pretreatment of the thymus DNA with deoxyribonuclease suppressed the DNA induced inhibition. Both ribonucleasetreated DNA and untreated DNA inhibited tumor growth.
摘要
先前与胸腺DNA一起孵育过的L1210白血病细胞的生长受到了抑制。在类似条件下，白血病细胞DNA并未影响肿瘤生长。用脱氧核糖核酸酶对胸腺DNA进行预处理可抑制DNA诱导的抑制作用。经核糖核酸酶处理的DNA和未处理的DNA均抑制肿瘤生长。
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