Leeson T S
Can Med Assoc J. 1965 Oct 23;93(17):921-32.
The use of the electron microscope has added much to our knowledge of the cell. The fine structure of the component parts of the nucleus and the cytoplasm is described, and their functions are indicated. The nature and structural modifications of the plasma membrane are illustrated with particular reference to function. To illustrate the interrelationships of the nucleus and cytoplasm, the theory of protein secretion is discussed, the secretion of a particular protein or polypeptide being determined by a particular nucleotide sequence in the desoxyribonucleic acid of a chromosome, that is, by a gene. This information is transferred from nucleus to cytoplasm. It is in the cytoplasm that the majority of the work is performed while the nucleus directs the work of the cell.
电子显微镜的应用极大地增进了我们对细胞的了解。文中描述了细胞核和细胞质组成部分的精细结构，并指出了它们的功能。特别结合功能阐述了质膜的性质和结构修饰。为说明细胞核与细胞质的相互关系，讨论了蛋白质分泌理论，即特定蛋白质或多肽的分泌由染色体脱氧核糖核酸中的特定核苷酸序列（即基因）决定。该信息从细胞核传递至细胞质。大部分工作在细胞质中进行，而细胞核则指导细胞的工作。
