Vierhapper H, Waldhäusl W
Arzneimittelforschung. 1979;29(8):1175-7.
Succinamyl-arg-val-tyr-val-his-pro-phenylglycine acetate (succinamyl1-val5-phenylglycine acetate3-A II), an analogue of angiotensin II, has a pressor effect upon patients suffering from primary and secondary hypertension regardless of prevailing plasma renin concentration. It stimulates the release of aldosterone, whereas plasma renin concentration is not influenced. It is concluded, that this new analogue is, as far as its effect upon blood pressure and release of aldosterone in man is concerned, an agonist of angiotensin II.
琥珀酰 - 精氨酸 - 缬氨酸 - 酪氨酸 - 缬氨酸 - 组氨酸 - 脯氨酸 - 苯甘氨酸乙酸盐（琥珀酰1 - 缬氨酸5 - 苯甘氨酸乙酸盐3 - A II），一种血管紧张素II的类似物，无论患者血浆肾素浓度如何，对原发性和继发性高血压患者均有升压作用。它刺激醛固酮的释放，而血浆肾素浓度不受影响。由此得出结论，就其对人体血压和醛固酮释放的影响而言，这种新的类似物是血管紧张素II的激动剂。
