Serebrovskaia I A, Biul' E V, Baimanova Kh M, Karpuk V I, Vakhrushev B N
Biull Eksp Biol Med. 1979 Dec;88(12):648-50.
The effect of the main blood constituents on surface activity of substrates containing pulmonary surfactant has been investigated. Mixing of hemolysate, serum, albumin, and fibrinogen with lung extracts and washings, their application in the form of a monolayer or administration into the hypophase of the washing monolayer raised the surface tension (ST) of these substrates. Hemoglobin, serum lipids and cholesterol exerted an opposite action. The contact of all above blood constituents, that elicited varied effects on the ST of the medium containing the surfactant with pulmonary vesicles led to an increase in their stability coefficient determined according to the method of Pattle.
研究了主要血液成分对含肺表面活性物质底物表面活性的影响。将溶血产物、血清、白蛋白和纤维蛋白原与肺提取物及洗液混合，以单层形式应用或将其加入洗液单层的下相，会提高这些底物的表面张力（ST）。血红蛋白、血清脂质和胆固醇则产生相反的作用。所有上述血液成分与含有肺小泡表面活性物质的介质的ST产生不同影响的接触，导致根据帕特尔方法测定的其稳定性系数增加。
