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Effect of gamma radiation on dietary and hormonal induction of enzymes in rat liver.

作者信息

Pitot H C, Peraino C, Lamar C

出版信息

Science. 1965 Nov 12;150(3698):901-3. doi: 10.1126/science.150.3698.901.

DOI:10.1126/science.150.3698.901
PMID:5835791
Abstract

The dietary induction of serine dehydrase, produced by the oral intubation of hydrolyzed casein to protein-depleted rats, is markedly inhibited by doses of gamma-radiation of 400 roentgens or higher provided the irradiation is given within an hour after the initial dose of casein. If the irradiation is delayed until 7 hours after the initial dose of casein, induction is not inhibited. In contrast, the cortisone induction of tyrosine alpha-ketoglutarate transaminase is not inhibited by doses of gamma-radiation up to 3200 roentgens; in some instances hormonal induction of this enzyme appears to be enhanced by irradiation.

摘要

相似文献

1
Effect of gamma radiation on dietary and hormonal induction of enzymes in rat liver.
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引用本文的文献

1
Time-dependence of the effect of X-irradiation on the formation of glycerol phosphate dehydrogenase and other dehydrogenases in the developing rat brain.X射线辐射对发育中大鼠大脑甘油磷酸脱氢酶及其他脱氢酶形成影响的时间依赖性
Biochem J. 1968 Mar;107(2):259-64. doi: 10.1042/bj1070259.
2
The effect of whole-body x-irradiation of guinea pigs on liver ribonucleic acid synthesis.豚鼠全身X线照射对肝脏核糖核酸合成的影响。
Biochem J. 1970 Feb;116(3):503-14. doi: 10.1042/bj1160503.
3
Effects of irradiation and starvation on the regulation of rat liver enzymes.
辐射和饥饿对大鼠肝脏酶调节的影响。
Proc Natl Acad Sci U S A. 1966 Oct;56(4):1303-9. doi: 10.1073/pnas.56.4.1303.