Simpson W J, Orange R P
Can Med Assoc J. 1965 Dec 11;93(24):1237-42.
To demonstrate skeletal metastases before radiographic changes were apparent, Sr(85) scans were carried out on 46 patients who complained of sketetal pain but whose radiographs were negative. Positive scans were obtained in 34 patients, 20 of whom were subsequently shown to have metastases; three did not have skeletal metastases a year or more later; the outcome is unknown in 11 patients. Twelve patients had negative scans: three ultimately developed metastases, six did not, and three were inconclusive. Autoradiographs demonstrated Sr(85) concentrations in areas of reactive osteogenesis.Although not specific for skeletal metastases, Sr(85) scans are most helpful in substantiating this diagnosis when radiographic changes are absent.
为了在X线改变明显之前显示骨骼转移，对46例主诉骨骼疼痛但X线片阴性的患者进行了锶（85）扫描。34例患者扫描结果为阳性，其中20例随后被证实有转移；3例在一年或更长时间后未发生骨骼转移；11例患者的结果未知。12例患者扫描结果为阴性：3例最终发生转移，6例未发生，3例结果不确定。放射自显影片显示在反应性骨生成区域有锶（85）浓聚。虽然锶（85）扫描对骨骼转移不具有特异性，但在没有X线改变时，对证实这一诊断最有帮助。
