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The gem effect. II. The influence of 3-mono- and 3,3-disubstitution on the rates of solvolysis of mono-p-bromophenyl glutarate.

作者信息

Bruice T C, Bradbury W C

出版信息

J Am Chem Soc. 1965 Nov 5;87(21):4846-50. doi: 10.1021/ja00949a031.

DOI:10.1021/ja00949a031
PMID:5844459
Abstract
摘要

相似文献

1
The gem effect. II. The influence of 3-mono- and 3,3-disubstitution on the rates of solvolysis of mono-p-bromophenyl glutarate.宝石效应。II. 3-单取代和3,3-二取代对单对溴苯基戊二酸酯溶剂解速率的影响。
J Am Chem Soc. 1965 Nov 5;87(21):4846-50. doi: 10.1021/ja00949a031.
2
The gem effect. I. The influence of 3-substituents on the rates of solvolysis of glutaric anhydride. A conformational analysis.宝石效应。I. 3-取代基对戊二酸酐溶剂解速率的影响。构象分析。
J Am Chem Soc. 1965 Nov 5;87(21):4838-45. doi: 10.1021/ja00949a030.
3
The gem effect. 3. The influence of 3-mono- and 3-gem substitution on the acid dissociation constants of glutaric acid. A comparison of the sensitivity of delta-pK-a of dicarboxylic acids and the rate of ring closure of their monoesters to the intramolecular distance separating carboxyl functions.偕二取代效应。3. 3-单取代和3-偕二取代对戊二酸的酸解离常数的影响。二元羧酸的ΔpKa敏感性及其单酯的环化速率对分隔羧基官能团的分子内距离的比较。
J Am Chem Soc. 1965 Nov 5;87(21):4851-5. doi: 10.1021/ja00949a032.
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Transport of anionic drugs across the basolateral membrane of proximal S2 segments of the rabbit kidney. Inverse relationship between the affinity to the p-aminohippurate transport system and the transport rate.
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PREPARATIVE ENZYMATIC-SYNTHESIS OF THE THREO AND ERYTHRO ISOMERS OF GAMMA-HYDROXY-L-GLUTAMIC ACID.γ-羟基-L-谷氨酸苏式和赤藓糖型异构体的制备性酶促合成
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Increased glutarate production by blocking the glutaryl-CoA dehydrogenation pathway and a catabolic pathway involving L-2-hydroxyglutarate.通过阻断戊二酰辅酶 A 脱氢酶途径和涉及 L-2-羟基戊二酸的分解代谢途径来增加戊二酸的产量。
Nat Commun. 2018 May 29;9(1):2114. doi: 10.1038/s41467-018-04513-0.
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[EMPIRICAL REPRESENTATION OF THE RELATIONSHIP BETWEEN THE PAPER CHROMATOGRAPHIC BEHAVIOR AND STRUCTURE OF SOME PHYSIOLOGICALLY IMPORTANT, NON-VOLATILE ALIPHATIC CARBOXYLIC ACIDS)].[某些生理上重要的非挥发性脂肪族羧酸的纸色谱行为与结构之间关系的实验表征]
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The chemistry of fungi. 68. Absolute configuration of 2-isopropyl-2-methyl-succinic and -glutaric acids: some resultant stereochemical corrections.真菌的化学。68. 2-异丙基-2-甲基琥珀酸和戊二酸的绝对构型:一些由此产生的立体化学修正。
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[Preparation of 5,5,6-trimethyl-1,3-cyclohexadione (methyldimedone) and 2,3,3-trimethylglutaric acid].[5,5,6-三甲基-1,3-环己二酮(甲基二甲基酮)和2,3,3-三甲基戊二酸的制备]
Farmaco Sci. 1970 Nov;25(11):889-91.

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Rate acceleration by stereopopulation control: models for enzyme action.
通过立体化学控制实现速率加速:酶作用模型
Proc Natl Acad Sci U S A. 1970 Nov;67(3):1143-7. doi: 10.1073/pnas.67.3.1143.
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Why are enzymes macromolecules?
Naturwissenschaften. 1979 Oct;66(10):498-504. doi: 10.1007/BF00404859.