Cunningham A I
Can Med Assoc J. 1965 Nov 20;93(21):1105-9.
Computer analysis of the results of a mass tuberculosis survey of the population of Chatham city and Kent County, Ontario, was carried out to assess the efficacy of such surveys as a case-finding device. Six cases of active tuberculosis were found during the survey and approximately 50% of the 89,427 inhabitants of Chatham and Kent County were surveyed with radiographs and Heaf skin tests.A follow-up study of the Heaf test conducted in the public school of Wallaceburg detected 70 Heaf-positive children out of a total of 1190. These Heaf-positive children were further tested with a Mantoux test (5 T.U.) and chest radiography. Only 11 children of the original 70 were Mantoux-positive.These findings further support the hypothesis that the Heaf test, as now read, over-reads for M. tuberculosis infections.
对安大略省查塔姆市和肯特县人口进行大规模结核病调查的结果进行了计算机分析，以评估此类调查作为病例发现手段的有效性。在调查期间发现了6例活动性结核病病例，查塔姆市和肯特县的89427名居民中约50%接受了X光检查和希夫皮肤试验。在华莱士堡公立学校对希夫试验进行的一项后续研究中，在总共1190名儿童中检测出70名希夫试验呈阳性的儿童。这些希夫试验呈阳性的儿童进一步接受了结核菌素试验（5个结核菌素单位）和胸部X光检查。最初的70名儿童中只有11名结核菌素试验呈阳性。这些发现进一步支持了这样一种假设，即按照目前的判读方式，希夫试验对结核分枝杆菌感染的判读过度。
