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Increase in radiosensitivity to ionizing radiation related to replacement of thymidine in mammalian cells with 5-bromodeoxyuridine.

作者信息

Dewey W C, Humphrey R M

出版信息

Radiat Res. 1965 Dec;26(4):538-53.

PMID:5849707
Abstract
摘要

相似文献

1
Increase in radiosensitivity to ionizing radiation related to replacement of thymidine in mammalian cells with 5-bromodeoxyuridine.哺乳动物细胞中胸腺嘧啶核苷被5-溴脱氧尿苷取代后对电离辐射的放射敏感性增加。
Radiat Res. 1965 Dec;26(4):538-53.
2
Radiosensitization of X chromosome of Chinese hamster cells related to incorporation of 5-bromodeoxyuridine.
Science. 1966 Apr 22;152(3721):519-21. doi: 10.1126/science.152.3721.519.
3
The kinetics of chromatid aberrations induced in Chinese hamster cells by tritium-labeled thymidine.氚标记胸腺嘧啶核苷诱导中国仓鼠细胞染色单体畸变的动力学
Radiat Res. 1966 Aug;28(4):779-92.
4
[The effect of a fractionated dose of ultraviolet irradiation on mammalian chromosomes].[分次剂量紫外线照射对哺乳动物染色体的影响]
Dokl Akad Nauk SSSR. 1968;178(3):707-10.
5
The stage of chromosome duplication in the cell cycle as revealed by x-ray breakage and 3H-thymidine labeling.通过X射线断裂和3H-胸腺嘧啶核苷标记揭示的细胞周期中染色体复制阶段。
Chromosoma. 1967;21(4):369-86. doi: 10.1007/BF00336948.
6
Inhibition of ultraviolet-induced chromosome breaks by cysteamine in 5-bromouracil-substituted mammalian cells.半胱胺对5-溴尿嘧啶取代的哺乳动物细胞中紫外线诱导的染色体断裂的抑制作用。
Radiat Res. 1967 Oct;32(2):200-13.
7
Radiosensitivity of normal and 5-bromodeoxyuridine treated mammalian cells during different phases of the cell cycle.
Exp Cell Res. 1965 Sep;39(2):483-95. doi: 10.1016/0014-4827(65)90052-2.
8
A comparison of unscheduled DNA synthesis, D 0 , cell recovery, and chromosome number in x-irradiated mammalian cell lines.对受X射线照射的哺乳动物细胞系中DNA非预定合成、D0、细胞恢复和染色体数目的比较。
Radiat Res. 1971 Aug;47(2):426-36.
9
On the formation of chromosomal aberrations.论染色体畸变的形成。
Mutat Res. 1970 Jan;9(1):117-26. doi: 10.1016/0027-5107(70)90075-8.
10
[Radioautographic study of chromosome reduplication in mammalian cells].[哺乳动物细胞染色体复制的放射自显影研究]
Tsitologiia. 1971;13(6):693-701.

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Quasi-Free Electron-Mediated Radiation Sensitization by C5-Halopyrimidines.C5-卤代嘧啶通过准自由电子介导的辐射增敏作用。
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Excited States of Bromopyrimidines Probed by VUV Photoabsorption Spectroscopy and Theoretical Calculations.溴代嘧啶激发态的真空紫外光吸收光谱和理论计算研究。
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Radiation-induced abnormalities in the chick embryos treated with urethane.用氨基甲酸乙酯处理的鸡胚中的辐射诱导异常。
Wilhelm Roux Arch Entwickl Mech Org. 1968 Dec;161(4):319-324. doi: 10.1007/BF00576683.
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Exposure to ionizing radiation reveals global dose- and time-dependent changes in the urinary metabolome of rat.暴露于电离辐射会揭示大鼠尿液代谢组中全局剂量和时间依赖性的变化。
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Bromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases.溴吡啶酮核苷酸类似物，通过聚合酶掺入DNA的缺氧选择性放射增敏剂。
J Org Chem. 2015 Nov 6;80(21):10675-85. doi: 10.1021/acs.joc.5b01833. Epub 2015 Oct 28.
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UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions.含卤代硫代嘧啶的DNA经紫外线A光激活会诱导产生细胞毒性DNA损伤。
J Photochem Photobiol B. 2015 Apr;145:1-10. doi: 10.1016/j.jphotobiol.2015.02.012. Epub 2015 Feb 20.
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Drug metabolism and homologous recombination repair in radiosensitization with gemcitabine.吉西他滨放射增敏中的药物代谢与同源重组修复
Radiat Res. 2015 Jan;183(1):114-23. doi: 10.1667/RR13807.1. Epub 2015 Jan 7.
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An ESR and DFT study of hydration of the 2'-deoxyuridine-5-yl radical: a possible hydroxyl radical intermediate.2'-脱氧尿苷-5-基自由基水合作用的电子自旋共振（ESR）和密度泛函理论（DFT）研究：一种可能的羟基自由基中间体
Chem Commun (Camb). 2014 Dec 4;50(93):14605-8. doi: 10.1039/c4cc07089e.
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Low-energy electron-induced damage in a trinucleotide containing 5-bromouracil.含 5-溴尿嘧啶的三核苷酸中低能电子诱导的损伤。
J Phys Chem B. 2011 Nov 24;115(46):13668-73. doi: 10.1021/jp205194g. Epub 2011 Nov 1.
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Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library.通过对化学文库的无偏向筛选鉴定一种新型强效小分子辐射增敏剂并进行生物学评估。
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