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1
The effects of solvent environment on the optical rotatory dispersion parameters of polypeptides. I. Studies on poly-gamma-benzyl-L-glutamate.溶剂环境对多肽旋光色散参数的影响。I. 聚-γ-苄基-L-谷氨酸的研究。
Biophys J. 1965 Jul;5(4):553-71. doi: 10.1016/S0006-3495(65)86734-0.
2
The effects of solvent environment on the optical rotatory dispersion parameters of polypeptides. II. Studies on poly-L-glutamic acid.溶剂环境对多肽旋光色散参数的影响。II. 聚-L-谷氨酸的研究。
Biophys J. 1965 Jul;5(4):573-89. doi: 10.1016/S0006-3495(65)86735-2.
3
Intrinsic birefringence of poly-gamma-benzyl-L-glutamate, a helical polypeptide, and the theory of birefringence.螺旋状多肽聚-γ-苄基-L-谷氨酸的固有双折射及双折射理论
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4
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INFLUENCE OF HELIX CONTENT AND SOLVENT ENVIRONMENT ON THE OPTICAL ROTATORY DISPERSION PARAMETERS OF POLYPEPTIDES.
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引用本文的文献

1
Analysis of Cotton-effect distribution of optical rotatory dispersion for polypeptides in solution.溶液中多肽旋光色散的科顿效应分布分析。
Biophysik. 1970;7(1):8-16. doi: 10.1007/BF01189457.
2
Protein conformations in cellular membranes.细胞膜中的蛋白质构象
Proc Natl Acad Sci U S A. 1966 Nov;56(5):1552-9. doi: 10.1073/pnas.56.5.1552.

本文引用的文献

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THE SOLUTION PROPERTIES AND CONFIGURATIONS OF A POLYAMPHOLYTIC POLYPEPTIDE: COPOLY-L-LYSINE-L-GLUTAMIC ACID.一种聚两性电解质多肽：聚-L-赖氨酸-L-谷氨酸的溶液性质与构型
Proc Natl Acad Sci U S A. 1958 May;44(5):424-31. doi: 10.1073/pnas.44.5.424.
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THE ULTRAVIOLET CIRCULAR DICHROISM OF POLYPEPTIDES.多肽的紫外圆二色性
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AN ANALYSIS OF THE OPTICAL ROTATORY DISPERSION OF POLYPEPTIDES AND PROTEINS.多肽与蛋白质的旋光色散分析
Proc Natl Acad Sci U S A. 1964 Apr;51(4):695-702. doi: 10.1073/pnas.51.4.695.
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CONFORMATIONAL STUDIES ON SYNTHETIC POLY-ALPHA-AMINO ACIDS: FACTORS INFLUENCING THE STABILITY OF THE HELICAL CONFORMATION OF POLY-L-GLUTAMIC ACID AND COPOLYMERS OF L-GLUTAMIC ACID AND L-LEUCINE.合成聚α-氨基酸的构象研究：影响聚-L-谷氨酸及L-谷氨酸与L-亮氨酸共聚物螺旋构象稳定性的因素
Biochemistry. 1964 Feb;3:155-66. doi: 10.1021/bi00890a004.
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INFLUENCE OF HELIX CONTENT AND SOLVENT ENVIRONMENT ON THE OPTICAL ROTATORY DISPERSION PARAMETERS OF POLYPEPTIDES.
J Mol Biol. 1963 Nov;7:590-8. doi: 10.1016/s0022-2836(63)80105-9.
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Optical rotatory dispersion and infrared studies of Beta-structures of Poly-O-benzyl-L-serine in solution.
J Mol Biol. 1962 Nov;5:487-96. doi: 10.1016/s0022-2836(62)80121-1.
7
Optical rotation and the conformation of polypeptides and proteins.多肽和蛋白质的旋光性与构象
Adv Protein Chem. 1961;16:401-544. doi: 10.1016/s0065-3233(08)60033-9.
8
Statistical evaluation of the rotatory dispersion parameters for helical polymers and proteins: two proposed methods and their application to data on polyglutamic acid and plasma albumin.
Arch Biochem Biophys. 1963 Feb;100:260-9. doi: 10.1016/0003-9861(63)90070-5.
9
The optical rotatory dispersion of right-handed alpha-helices in sperm whale myoglobin.抹香鲸肌红蛋白中右手α-螺旋的旋光色散
Proc Natl Acad Sci U S A. 1961 Oct 15;47(10):1635-41. doi: 10.1073/pnas.47.10.1635.
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Rotatory behavior of protein denaturation.蛋白质变性的旋转行为。
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溶剂环境对多肽旋光色散参数的影响。I. 聚-γ-苄基-L-谷氨酸的研究。

The effects of solvent environment on the optical rotatory dispersion parameters of polypeptides. I. Studies on poly-gamma-benzyl-L-glutamate.

作者信息

Cassim J Y, Taylor E W

出版信息

Biophys J. 1965 Jul;5(4):553-71. doi: 10.1016/S0006-3495(65)86734-0.

DOI:10.1016/S0006-3495(65)86734-0
PMID:5861706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1367892/
Abstract

The constancy of the Moffitt optical rotatory dispersion parameters for polypeptides in different solvents was tested by dispersion measurements on poly-gamma-benzyl-L-glutamate in fifty-five solvents and solvent mixtures. b(0) was not constant but varied linearly with the refractive index of the solvent according to the equation -b(0) = 1701 - 730.3 n(8). This variation could not be explained by changes in configuration of the polypeptide. a(0) also showed a trend with solvent index but the values were widely scattered. lambda(0) did not show a statistically significant dependence on solvent index. The variation in b(0) can be interpreted as an effect of solvent polarizability on the frequencies of optically active transitions.

摘要

通过对聚-γ-苄基-L-谷氨酸在55种溶剂和溶剂混合物中的色散测量，测试了莫菲特（Moffitt）旋光色散参数在不同溶剂中对多肽的恒定性。b(0)并非恒定不变，而是根据方程-b(0) = 1701 - 730.3 n(8)随溶剂折射率呈线性变化。这种变化无法用多肽构型的改变来解释。a(0)也随溶剂指数呈现出一种趋势，但数值分布广泛。λ(0)对溶剂指数没有显示出统计学上的显著依赖性。b(0)的变化可以解释为溶剂极化率对旋光跃迁频率的影响。