沙利度胺作为一种潜在的生物酰化剂。 - Suppr

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超能文献

Thalidomide as a possible biological acylating agent.

作者信息

Fabro S, Smith R L, Williams R T

出版信息

Nature. 1965 Dec 18;208(5016):1208-9. doi: 10.1038/2081208a0.

DOI:10.1038/2081208a0

PMID:5870320

Abstract

摘要

相似文献

Thalidomide as a possible biological acylating agent.沙利度胺作为一种潜在的生物酰化剂。

Nature. 1965 Dec 18;208(5016):1208-9. doi: 10.1038/2081208a0.

The metabolism of thalidomide: some biological effects of thalidomide and its metabolites.沙利度胺的代谢：沙利度胺及其代谢产物的一些生物学效应。

Br J Pharmacol Chemother. 1965 Oct;25(2):352-62. doi: 10.1111/j.1476-5381.1965.tb02055.x.

[Experimental studies with cyclic imides. V. Cleavage of the phthalimide ring in thalidomide by amines].[环状酰亚胺的实验研究。V. 胺对沙利度胺中邻苯二甲酰亚胺环的裂解]

Arzneimittelforschung. 1968 Oct;18(10):1313-7.

The metabolism of thalidomide: the spontaneous hydrolysis of thalidomide in solution.沙利度胺的代谢：沙利度胺在溶液中的自发水解。

Br J Pharmacol Chemother. 1965 Oct;25(2):324-37. doi: 10.1111/j.1476-5381.1965.tb02053.x.

Chemical structure and teratogenic properties. IV. An outline of a chemical hypothesis for the teratogenic action of thalidomide.化学结构与致畸特性。IV. 关于沙利度胺致畸作用的化学假说概述。

Acta Pharm Suec. 1972 Dec;9(6):543-62.

The metabolism of thalidomide: the fate of thalidomide and some of its hydrolysis products in various species.沙利度胺的代谢：沙利度胺及其某些水解产物在不同物种中的命运。

Br J Pharmacol Chemother. 1965 Oct;25(2):338-51. doi: 10.1111/j.1476-5381.1965.tb02054.x.

[Imidazole and thalidomide. Interaction of purine bases and the phthalamide nucleus].[咪唑与沙利度胺。嘌呤碱与邻苯二甲酰胺核的相互作用]

Bull Acad Natl Med. 1966 Mar 8;150(9):137-42.

[ON THE SOLUBILITY OF CONTERGAN].

Farm Zh. 1964;19:69-72.

Thalidomide solutions.沙利度胺溶液

Science. 1966 Dec 9;154(3754):1362.

[Should thalidomide be rehabilitated?].[沙利度胺应被恢复使用吗？]

Sem Hop. 1983 Dec 8;59(45):3101-4.

引用本文的文献

Possible involvement of an acylation mechanism in thalidomide-induced teratogenesis of the newt (Pleurodeles waltl.).酰化机制可能参与沙利度胺诱导的蝾螈（Pleurodeles waltl.）致畸作用。

Dev Growth Differ. 1996 Feb;38(1):47-57. doi: 10.1046/j.1440-169X.1996.00007.x.

Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model.沙利度胺在人源化CYP3A小鼠模型中诱导的肢体异常。

Sci Rep. 2016 Feb 23;6:21419. doi: 10.1038/srep21419.

Thalidomide increases human hepatic cytochrome P450 3A enzymes by direct activation of the pregnane X receptor.沙利度胺通过直接激活孕烷 X 受体增加人肝细胞色素 P450 3A 酶。

Chem Res Toxicol. 2014 Feb 17;27(2):304-308. doi: 10.1021/tx4004374. Epub 2014 Feb 5.

Human cytochrome P450 oxidation of 5-hydroxythalidomide and pomalidomide, an amino analogue of thalidomide.人细胞色素P450对5-羟基沙利度胺和泊马度胺（沙利度胺的氨基类似物）的氧化作用。

Chem Res Toxicol. 2014 Jan 21;27(1):147-56. doi: 10.1021/tx4004215. Epub 2013 Dec 24.

Human liver microsomal cytochrome P450 3A enzymes involved in thalidomide 5-hydroxylation and formation of a glutathione conjugate.涉及沙利度胺 5-羟化和形成谷胱甘肽缀合物的人肝微粒体细胞色素 P450 3A 酶。

Chem Res Toxicol. 2010 Jun 21;23(6):1018-24. doi: 10.1021/tx900367p.

The hydrolysis of polyimides.

Experientia. 1973 Aug 15;29(8):962-4. doi: 10.1007/BF01930403.

Accumulation of calcium and phosphate stimulated by carboxylic antibiotics into mitochondria.羧基抗生素刺激钙和磷酸盐在线粒体中积累。

J Bioenerg. 1972 Aug;3(5):361-75. doi: 10.1007/BF01516075.

Thalidomide neuropathy: a clinical electrophysiological, and histological follow-up study.沙利度胺神经病变：一项临床、电生理及组织学随访研究。

J Neurol Neurosurg Psychiatry. 1968 Dec;31(6):543-51. doi: 10.1136/jnnp.31.6.543.

[Embryotoxicity and teratogenicity of derivatives of 1,3-indandion (author's transl)].

Arch Toxicol. 1975;33(3):191-7. doi: 10.1007/BF00311272.

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