Haselby R C
J Am Osteopath Assoc. 1977 Apr;76(8):605-16.
Rational antimicrobial therapy depends on the identity of the causative organisms, the location of the infection, and the condition of the host. Selection of antimicrobial therapy is often started before identification of the causative organism is complete. Certain cultural and staining procedures must be instigated prior to therapy in order to isolate the causative organism. Knowledge of the host's physiologic state is necessary to minimize toxicities and/or failures of therapy. Knowledge of synergistic and antagonistic actions of some antimicrobial agents is necessary for optimal results.
合理的抗菌治疗取决于病原体的种类、感染部位以及宿主的状况。在病原体鉴定完成之前，通常就开始选择抗菌治疗。在治疗前必须采用某些培养和染色程序，以便分离出病原体。了解宿主的生理状态对于将治疗的毒性和/或失败降至最低是必要的。了解某些抗菌药物的协同和拮抗作用对于取得最佳疗效是必要的。
