Shubich M G, Mogil'naia G M, Fisher A A
Arkh Patol. 1977;39(9):49-55.
The results of the study suggest that the secrete of the gastric lining epithelium of man and dog contains a free cation protein which is a macromolecular ingredient of the alkaline component of gastric juice. Under conditions of increasing and persisting hypersecretion of the acid, first the surface and then the pit epithelium increasingly secrete cation protein, and in the gastric juice an increased content of the alkaline component is detected. Subsequently, with persisting hypersecretion, the synthesizing capacity of the epithelial cells is exhausted and this is accompanied by a deficiency of the alkaline component in gastric juice.
研究结果表明,人和狗胃黏膜上皮的分泌物中含有一种游离阳离子蛋白,它是胃液碱性成分的大分子成分。在胃酸分泌持续增加的情况下,首先是表面上皮,然后是胃小凹上皮会越来越多地分泌阳离子蛋白,并且在胃液中检测到碱性成分的含量增加。随后,随着胃酸分泌持续增加,上皮细胞的合成能力耗尽,同时胃液中碱性成分缺乏。