醋酸甲地孕酮（17-α-乙酰氧基-6-甲基孕甾-4,6-二烯-3,20-二酮）在兔体内的代谢 - Suppr | 超能文献

The metabolism of megestrol acetate (17-alpha-acetoxy-6-methylpregna-4, 6-diene-3, 20-dione) in the rabbit.

作者信息

Cooper J M, Jones H E, Kellie A E

出版信息

Steroids. 1965 Sep;6(3):255-75. doi: 10.1016/0039-128x(65)90003-6.

DOI:10.1016/0039-128x(65)90003-6

Abstract

摘要

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The metabolism of megestrol acetate (17-alpha-acetoxy-6-methylpregna-4, 6-diene-3, 20-dione) in the rabbit.醋酸甲地孕酮（17-α-乙酰氧基-6-甲基孕甾-4,6-二烯-3,20-二酮）在兔体内的代谢

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Metabolism of megestrol acetate by rat adrenal glands in vitro.醋酸甲地孕酮在大鼠肾上腺体外的代谢

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Plasma levels of megestrol acetate.醋酸甲地孕酮的血浆水平。

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Sustained release hormonal preparations. 9. Plasma levels and accumulation into various tissues of 6-methyl-17 alpha-acetoxy-4,6-pregnadiene-3,20-dione after oral administration or absorption from polydimethylsiloxane implants.缓释激素制剂。9. 口服给药或从聚二甲基硅氧烷植入物吸收后6-甲基-17α-乙酰氧基-4,6-孕二烯-3,20-二酮的血浆水平及在各组织中的蓄积情况。

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Synthesis of [6-methyl-14-C]megestrol acetate (17-alpha-acetoxy-6[14-C]-methylpregna-4,6-diene-3,20-dione).[6-甲基-¹⁴C]甲地孕酮醋酸酯（17-α-乙酰氧基-6-[¹⁴C]-甲基孕甾-4,6-二烯-3,20-二酮）的合成

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Synthesis of [1,2-3H2]medroxyprogesterone acetate (17-alpha-acetoxy-6-alpha-methyl[1,2-3H2]pregn-4-ene-3,20-dione) and [1,2-3H2]megestrol acetate (17-alpha-acetoxy-6-methyl[1,2-3H2]pregna-4,6-diene-3,20-dione).[1,2-³H₂]醋酸甲羟孕酮（17-α-乙酰氧基-6-α-甲基[1,2-³H₂]孕-4-烯-3,20-二酮）和[1,2-³H₂]醋酸甲地孕酮（17-α-乙酰氧基-6-甲基[1,2-³H₂]孕-4,6-二烯-3,20-二酮）的合成

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Modified steroid hormones. XLII. Partial synthesis of 17-alpha-acetoxy-6-acetoxymethylpregna 4,6-diene-3,20-dione and its 2-alpha-acetoxy derivative, two acetylated metabolites of megestrol acetate.修饰的甾体激素。XLII. 17-α-乙酰氧基-6-乙酰氧甲基孕甾-4,6-二烯-3,20-二酮及其2-α-乙酰氧基衍生物（醋酸甲地孕酮的两种乙酰化代谢物）的部分合成

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引用本文的文献

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Plasma levels of megestrol acetate.醋酸甲地孕酮的血浆水平。

Biochem J. 1967 Sep;104(3):58P.

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The metabolism of melengestrol acetate.醋酸美仑孕酮的代谢

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Metabolism of megestrol acetate by rat adrenal glands in vitro.醋酸甲地孕酮在大鼠肾上腺体外的代谢

Biochem J. 1968 Aug;109(1):121-5. doi: 10.1042/bj1090121.