细菌中精氨酸生物合成的特定途径调控模式。
Pathway-specific pattern of control of arginine biosynthesis in bacteria.
作者信息
Udaka S
出版信息
J Bacteriol. 1966 Feb;91(2):617-21. doi: 10.1128/jb.91.2.617-621.1966.
Abstract
Udaka, Shigezo (The Institute of Physical and Chemical Research, Komagome, Bunkyo-ku, Tokyo, Japan). Pathway-specific pattern of control of arginine biosynthesis in bacteria. J. Bacteriol. 91:617-621. 1966.-To compare control mechanisms of arginine biosynthesis in various bacteria, activities of several enzymes of the arginine pathway were measured in cells cultivated under repressed and partially derepressed conditions. Nineteen strains of bacteria tested appeared to have two types of pathways, closely related to each other. The partially derepressed levels of enzymes varied from bacterium to bacterium. The degree of inhibition of enzyme 2 (the second of eight enzymes concerned with arginine biosynthesis) and the repressibility of enzymes by arginine also appeared to vary from species to species. On the other hand, enzyme 2 was found to be the site of end-product inhibition only in the bacteria having a particular pathway. These results suggest that the bacteria have their own species-specific control mechanisms and that there is a pathway-specific pattern of control in arginine biosynthesis. The implications of the results are discussed from the viewpoint of evolution of control mechanisms.
摘要
uda ka，重三（日本东京文京区小宫町理化研究所）。细菌中精氨酸生物合成的途径特异性调控模式。《细菌学杂志》91:617 - 621。1966年。——为比较不同细菌中精氨酸生物合成的调控机制，在阻遏和部分去阻遏条件下培养的细胞中测量了精氨酸途径中几种酶的活性。测试的19种细菌菌株似乎有两种彼此密切相关的途径。酶的部分去阻遏水平因细菌而异。酶2（与精氨酸生物合成相关的八种酶中的第二种）的抑制程度以及精氨酸对酶的阻遏能力似乎也因物种而异。另一方面，仅在具有特定途径的细菌中发现酶2是终产物抑制的位点。这些结果表明细菌具有其自身物种特异性的调控机制，并且在精氨酸生物合成中存在途径特异性的调控模式。从调控机制进化的角度讨论了这些结果的意义。
相似文献
1
Pathway-specific pattern of control of arginine biosynthesis in bacteria.细菌中精氨酸生物合成的特定途径调控模式。
J Bacteriol. 1966 Feb;91(2):617-21. doi: 10.1128/jb.91.2.617-621.1966.
2
Concerted repression of the synthesis of the arginine biosynthetic enzymes by aminoacids: a comparison between the regulatory mechanisms controlling aminoacid biosyntheses in bacteria and in yeast.氨基酸对精氨酸生物合成酶合成的协同抑制：细菌和酵母中控制氨基酸生物合成的调控机制之比较
Mol Gen Genet. 1979 Jan 16;169(1):85-95. doi: 10.1007/BF00267549.
3
Organization and control in the arginine biosynthetic pathway of Neurospora.粗糙脉孢菌精氨酸生物合成途径中的组织与调控
J Bacteriol. 1975 Jul;123(1):196-202. doi: 10.1128/jb.123.1.196-202.1975.
4
Regulation of enzyme synthesis in the arginine biosynthetic pathway of Pseudomonas aeruginosa.铜绿假单胞菌精氨酸生物合成途径中酶合成的调控
J Gen Microbiol. 1978 Nov;109(1):25-35. doi: 10.1099/00221287-109-1-25.
5
Regulation of arginine biosynthesis in the psychropiezophilic bacterium Moritella profunda: in vivo repressibility and in vitro repressor-operator contact probing.嗜冷菌深海底栖莫里塔氏菌中精氨酸生物合成的调控：体内可阻遏性及体外阻遏物-操纵基因接触探测
J Mol Biol. 2003 Feb 14;326(2):353-69. doi: 10.1016/s0022-2836(02)01375-x.
6
Explanation for different types of regulation of arginine biosynthesis in Escherichia coli B and Escherichia coli K12 caused by a difference between their arginine repressors.对大肠杆菌B和大肠杆菌K12中精氨酸生物合成不同调控类型的解释，这是由它们的精氨酸阻遏物之间的差异所导致的。
J Mol Biol. 1994 Jan 7;235(1):221-30. doi: 10.1016/s0022-2836(05)80028-2.
7
Studies on the mechanism of repression of arginine biosynthesis in Escherichia coli. IV. Further studies on the role of arginine transfer RNA repression of the enzymes of arginine biosynthesis.大肠杆菌中精氨酸生物合成抑制机制的研究。IV. 关于精氨酸转移RNA对精氨酸生物合成酶抑制作用的进一步研究。
J Mol Biol. 1971 Nov 28;62(1):179-88. doi: 10.1016/0022-2836(71)90138-0.
8
Repression of enzymes of arginine biosynthesis by L-canavanine in arginyl-transfer ribonucleic acid synthetase mutants of Escherichia coli.L-刀豆氨酸对大肠杆菌精氨酰转移核糖核酸合成酶突变体中精氨酸生物合成酶的抑制作用。
J Bacteriol. 1972 Oct;112(1):102-13. doi: 10.1128/jb.112.1.102-113.1972.
9
Studies on the mechanism of repression of arginine biosynthesis in Escherichia coli. 3. Repression of enzymes of arginine biosynthesis in arginyl-tRNA synthetase mutants.大肠杆菌中精氨酸生物合成抑制机制的研究。3. 精氨酰 - tRNA合成酶突变体中精氨酸生物合成酶的抑制作用。
J Mol Biol. 1968 Jul 14;35(1):83-93. doi: 10.1016/s0022-2836(68)80038-5.
10
General control of arginine biosynthetic enzymes in Neurospora crassa.粗糙脉孢菌中精氨酸生物合成酶的总体调控
J Gen Microbiol. 1981 May;124(1):129-40. doi: 10.1099/00221287-124-1-129.
引用本文的文献
1
Functional Analysis of Feedback Inhibition-Insensitive Variants of -Acetyl Glutamate Kinase Found in Sake Yeast Mutants with Ornithine Overproduction.在具有鸟氨酸过量生产的清酒酵母突变体中发现的 - 乙酰谷氨酸激酶反馈抑制不敏感变体的功能分析。
Microbiol Spectr. 2022 Jun 29;10(3):e0082222. doi: 10.1128/spectrum.00822-22. Epub 2022 May 11.
2
Production of l-glutamate family amino acids in : Physiological mechanism, genetic modulation, and prospects.L-谷氨酸家族氨基酸的生产：生理机制、遗传调控及前景
Synth Syst Biotechnol. 2021 Sep 20;6(4):302-325. doi: 10.1016/j.synbio.2021.09.005. eCollection 2021 Dec.
3
Improvement of L-citrulline production in Corynebacterium glutamicum by ornithine acetyltransferase.通过鸟氨酸乙酰转移酶提高谷氨酸棒杆菌中L-瓜氨酸的产量
J Ind Microbiol Biotechnol. 2015 Feb;42(2):307-13. doi: 10.1007/s10295-014-1561-x. Epub 2014 Dec 10.
4
Metabolic engineering of microorganisms for the production of L-arginine and its derivatives.用于生产L-精氨酸及其衍生物的微生物代谢工程。
Microb Cell Fact. 2014 Dec 3;13:166. doi: 10.1186/s12934-014-0166-4.
5
A novel type of N-acetylglutamate synthase is involved in the first step of arginine biosynthesis in Corynebacterium glutamicum.一种新型的N-乙酰谷氨酸合酶参与谷氨酸棒杆菌中精氨酸生物合成的第一步。
BMC Genomics. 2013 Oct 18;14:713. doi: 10.1186/1471-2164-14-713.
6
Intestinal microbiome and digoxin inactivation: meal plan for digoxin users?肠道微生物组与地高辛失活：地高辛使用者的饮食计划？
World J Microbiol Biotechnol. 2014 Mar;30(3):791-9. doi: 10.1007/s11274-013-1507-x. Epub 2013 Oct 9.
7
Purification and characterization of an arginine regulatory protein, ArgR, in Corynebacterium glutamicum.在谷氨酸棒杆菌中精氨酸调节蛋白 ArgR 的纯化和表征。
J Ind Microbiol Biotechnol. 2011 Dec;38(12):1911-20. doi: 10.1007/s10295-011-0977-9. Epub 2011 May 11.
8
Surprising arginine biosynthesis: a reappraisal of the enzymology and evolution of the pathway in microorganisms.惊人的精氨酸生物合成：对微生物中该途径的酶学和进化的重新评估。
Microbiol Mol Biol Rev. 2007 Mar;71(1):36-47. doi: 10.1128/MMBR.00032-06.
9
Formation of N-acetylglutamate by extracts of higher plants.高等植物提取物中 N-乙酰谷氨酸的形成。
Plant Physiol. 1977 Apr;59(4):684-7. doi: 10.1104/pp.59.4.684.
10
Feedback regulation of arginine biosynthesis in blue-green algae and photosynthetic bacteria.蓝藻和光合细菌中精氨酸生物合成的反馈调节。
J Bacteriol. 1966 Aug;92(2):375-9. doi: 10.1128/jb.92.2.375-379.1966.
本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
ALTERNATIVE PATTERNS OF END-PRODUCT CONTROL IN BIOSYNTHESIS OF AMINO-ACIDS OF THE ASPARTIC FAMILY.天冬氨酸族氨基酸生物合成中终产物控制的替代模式。
Nature. 1964 Sep 19;203:1259-61. doi: 10.1038/2031259a0.
3
END-PRODUCT INHIBITION OF ASPARTATE TRANSCARBAMYLASE IN VARIOUS SPECIES.不同物种中天冬氨酸转氨甲酰酶的终产物抑制作用
Arch Biochem Biophys. 1964 Mar;104:438-47. doi: 10.1016/0003-9861(64)90487-4.
4
A COMPARATIVE STUDY OF THE REGULATION OF PYRIDINE NUCLEOTIDE FORMATION.吡啶核苷酸形成调控的比较研究
Biochim Biophys Acta. 1964 Mar 16;82:445-53. doi: 10.1016/0304-4165(64)90436-2.
5
[BIOSYNTHESIS OF ARGININE IN YEAST. I. THE FATE OF N-ALPHA-ACETYLORNITHINE].[酵母中精氨酸的生物合成。I. N-α-乙酰鸟氨酸的去向]
Biochim Biophys Acta. 1963 Dec 13;78:606-16. doi: 10.1016/0006-3002(63)91026-6.
6
THE ORNITHINE PATHWAY IN THE YEAST CANDIDA UTILIS.产朊假丝酵母中的鸟氨酸途径。
Biochim Biophys Acta. 1963 Sep 3;77:152-4. doi: 10.1016/0006-3002(63)90482-7.
7
Feedback inhibition of acetylglutamate synthetase by arginine in Escherichia coli.精氨酸对大肠杆菌中乙酰谷氨酸合成酶的反馈抑制作用。
Arch Biochem Biophys. 1963 Mar;100:542-6. doi: 10.1016/0003-9861(63)90124-3.
8
Acetylated intermediates of arginine synthesis in Bacillus subtilis.枯草芽孢杆菌中精氨酸合成的乙酰化中间体。
Biochim Biophys Acta. 1963 Jan 1;69:174-6. doi: 10.1016/0006-3002(63)91241-1.
9
Aspects of repression in the regulation of enzyme synthesis: pathway-wide control and enzyme-specific response.酶合成调控中的阻遏作用：全途径控制与酶特异性反应
Cold Spring Harb Symp Quant Biol. 1961;26:163-72. doi: 10.1101/sqb.1961.026.01.021.
10
Genetics of regulation of enzyme synthesis in the arginine biosynthetic pathway of Escherichia coli.大肠杆菌精氨酸生物合成途径中酶合成调控的遗传学
Cold Spring Harb Symp Quant Biol. 1961;26:173-82. doi: 10.1101/sqb.1961.026.01.022.
Zotero 插件