Gudelsky G A, Annunziato L, Moore K E
Endocrinology. 1977 Dec;101(6):1894-7. doi: 10.1210/endo-101-6-1894.
The norepinephrine (NE) and dopamine (DA) concentrations of the median eminence and the remaining hypothalamus of female rats were assayed using a sensitive radioenzymatic method. There were no changes in the catecholamine concentrations of either brain region when measured in the mornings of the different days of the estrous cycle. Four to 5 weeks after ovariectomy there was a marked increase in the DA but not the NE content of the median eminence, and the daily administration of estradiol benzoate for 7 days prior to sacrifice reversed the ovariectomy-induced increase in DA. Ovariectomy did not alter catecholamine concentrations in the remaining hypothalamus.
采用灵敏的放射酶法测定了雌性大鼠正中隆起和下丘脑其余部分的去甲肾上腺素(NE)和多巴胺(DA)浓度。在动情周期不同天数的上午进行测量时,两个脑区的儿茶酚胺浓度均无变化。卵巢切除术后4至5周,正中隆起的DA含量显著增加,但NE含量未增加,且在处死前连续7天每日给予苯甲酸雌二醇可逆转卵巢切除诱导的DA增加。卵巢切除术未改变下丘脑其余部分的儿茶酚胺浓度。